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目的:探讨精液处理后活动精子总数(PTMS)对宫腔内人工授精(IUI)妊娠成功率的影响。方法:回顾性分析372例不孕患者共816个IUI周期的临床资料。按照PTMS数量将IUI周期分成4个区间组:PTMS<3×106(A组),3×106-5×106(B组),5×106-10×106(C组),>10×106(D组),分别比较各组间的IUI周期妊娠率。结果:816个IUI周期共获得110例妊娠,总周期妊娠率为13.5%。不同PTMS分组的周期妊娠率分别为3.8%,4.2%,14.8%和14.3%。其中A组、B组的周期妊娠率均显著低于C组和D组(P<0.05)。结论:PTMS是男性生育力评估及助孕方式选择的重要参考依据。当PTMS超过5×106时,可首选IUI治疗。
Objective: To investigate the effect of total sperm motility (PTMS) on intrauterine insemination (IUI) pregnancy success rate. Methods: A retrospective analysis of 372 cases of infertility patients with a total of 816 IUI cycle clinical data. The IUI periods were divided into 4 intervals according to the number of PTMS: PTMS <3 × 106 (group A), 3 × 106-5 × 106 (group B), 5 × 106-10 × 106 (group C),> 10 × 106 (Group D), respectively, comparing the IUI cycle pregnancy rates among the groups. Results: A total of 110 pregnancies were obtained in 816 IUI cycles and the total cycle pregnancy rate was 13.5%. The cycle pregnancy rates for different PTMS groups were 3.8%, 4.2%, 14.8% and 14.3%, respectively. The pregnancy rates of group A and group B were significantly lower than those of group C and group D (P <0.05). Conclusion: PTMS is an important reference for evaluation of male fertility and choice of pregnancy-assisted methods. When PTMS exceeds 5 × 106, the preferred IUI treatment.