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采用ＲＩＡ法研究１３４例ＨＢＶ感染者及３６例健康者的血清ＨＢｃＡｇ与ＨＢｓＡｇ·Ｒｅ。结果：１１０例ＨＢｓＡｇ阳性者中，分别检出９５例ＨＢｃＡｇ阳性（占８６．４％），６９例的ＨＢｓＡｇ·Ｒｅ阳性（６２．７％）；３３例ＨＢｅＡｇ阳性者中，２９例检出ＨＢｃＡｇ阳性（８７．９％），２６例同时检出ＨＢｓＡｇ·Ｒｅ阳性（７８．８％）；４５例抗－ＨＢｅ阳性者中，４２例检测到ＨＢｃＡｇ阳性（９３．３％），２２例检测到ＨＢｓＡｇ·Ｒｅ阳性（４８．９％）；９７例抗－ＨＢｃ阳性者中（部分同时伴存ＨＢｅＡｇ阳性），测得９１例的ＨＢｃＡｇ阳性（９３．８％），测得６１例的ＨＢｓＡｇ·Ｒｅ阳性（６２．９％）。本研究从临床角度证实，ＨＢｃＡｇ与ＨＢｓＡｇ·Ｒｅ血清学检测阳性，皆为乙型病毒性肝炎具有传染性以及ＨＢＶ活动性复制的既可靠且又敏感度高的标志。
RIA was used to study the serum HBcAg and HBsAg · Re in 134 HBV infected patients and 36 healthy controls. Results: Of the 110 cases of HBsAg positive, 95 cases were positive for HBcAg (86.4%) and 69 cases were positive for HBsAg Re (62.7%). Of 33 HBeAg positive cases, 29 cases were positive for HBcAg (87.9%) were positive in 26 cases and positive in HBsAg Re was detected in 26 cases (78.8%). Of 45 anti-HBe positive cases, 42 cases were positive for HBcAg (93.3%) and 22 cases were detected HBsAg Re positive (48.9%); 97 cases of anti-HBc positive (some concurrent with HBeAg positive), 91 cases of HBcAg positive (93.8%) were measured in 61 cases of HBsAg Re Positive (62.9%). This study confirmed from the clinical point of view, HBcAg and HBsAg · Re serological test were positive for both hepatitis B virus infection and HBV activity replication of both reliable and sensitive markers.