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Horton 氏病或巨细胞性动脉炎的临床表现尽人皆知。在皮质激素问世之前,10%因心脑血管并发症致死,30～50%失明。自激素疗法开展以来,治疗逾1年者失明已罕见,死亡率与一般人群者无异。然文献中对激素疗法的过程和停用激素后的转归则鲜有报道。本文介绍1970—1984年5个不同专科(内科、风湿科、传染病科、神经内科、眼科)临床所见87例经病理切片证实并且长期随诊的巨细胞性动脉炎的回顾性分析。
The clinical manifestations of Horton’s disease or giant cell arteritis are well known. Before the advent of corticosteroids, 10% died of cardiovascular and cerebrovascular complications, 30 to 50% of blindness. Since the hormone therapy started, the treatment of blindness for more than one year has been rare, the mortality rate is no different from the general population. However, the literature on the hormone therapy process and the withdrawal of hormones after the transfer is rarely reported. This article presents a retrospective analysis of 87 patients with pathologically confirmed and long-term follow-up of giant cell arteritis seen in five different specialist disciplines (internal medicine, rheumatology, infectious diseases, neurology, ophthalmology) from 1970 to 1984.