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用Ｅ．ｃｏｌｉ ＣＭ８９１ 菌株的正向突变（ＳＭｒ－ ５） 和回复突变（ＴｒＰ＋） 双重指标，以细胞内抗突变作用的模式检测了１６ 种中药水提取物的抗４ ＮＱＯ 的致突变活性。结果显示：诃子、首乌、女贞子和带蒂菱壳具有拮抗４ ＮＱＯ 诱发的正向突变和回复突变的作用；带蒂菱壳还具有抗自发正向和回复突变的作用。白芍具有促进４ ＮＱＯ 的致突变活性
Use E. The dual mutations of positive mutation (SMr-5) and reverse mutation (TrP+) of the coli CM891 strain detected the antimutagenic activity of 4 NQOs of the water extracts of 16 Chinese herbs using intracellular antimutagenic effects. The results showed that Xunzi, Shouwu, Ligustrum lucidum and pedicel shell have antagonistic effects on 4 NQO-induced positive mutations and back mutations; pedicel shells also have the ability to resist spontaneous positive and return mutations. White peony has the mutagenic activity to promote 4 NQO