用SOS显色法测定了复方赤芍、钩吻碱、罗汉金丹口服液与衡法Ⅱ号对MNNG、B(a)P、UV诱发大肠杆菌细胞SOS反应的抑制作用和抗突变作用。4种中药均以2.5、5.0、10.0mg/ml 3种浓度,在致突性试验、抗突变试验中与阳性对照组比较,显示无致突变与抗突变作用,但在抑制突变试验中,结果表明仅钩吻碱能抑制MNNG、UV所致的突变,而不能抑制B(a)P所致突变。 The inhibition and antimutagenic effect of compound Radix Paeoniae Rubra, Leucogeline, Luohan Jindan Oral Liquid and Hengfa II on SOM responses induced by MNNG, B(a)P and UV-induced E. coli cells were determined by SOS chromogenic assay. The four Chinese herbs were compared with the positive control group at concentrations of 2.5, 5.0, and 10.0 mg/ml in the bursting test and antimutation test, showing no mutagenic and antimutagenic effects, but in the inhibition mutation test, the results It was shown that only gloxinine can inhibit MNNG, UV-induced mutations but not B(a)P-induced mutations.