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目的探讨惊厥性癫持续状态的诊断及治疗方法,改善患者预后。方法回顾性分析27例惊厥性癫持续状态患者的临床资料。结果惊厥性癫持续状态其病因以脑血管病、特发性癫自行停药或减药、脑炎及脑外伤等为主;多数患者地西泮、丙戊酸、苯巴比妥钠等抗癫药物治疗有效,症状控制不良者给予丙泊酚可控制疾病发作;本组治愈23例,死亡3例,自动出院1例。结论癫持续状态多因脑血管病和特发性癫患者不规律服药所引起,脑炎及脑外伤也是常见病因;发作早期地西泮、苯巴比妥钠有良好治疗效果,丙泊酚可作为难治性癫持续状态的首选药物。
Objective To investigate the diagnosis and treatment of convulsive status epilepticus and to improve the prognosis of patients. Methods The clinical data of 27 patients with convulsive status epilepticus were retrospectively analyzed. Results Seizure persistence of epilepsy etiology due to cerebrovascular disease, idiopathic epilepsy self-withdrawal or reduction of drugs, encephalitis and traumatic brain injury; the majority of patients with diazepam, valproic acid, phenobarbital sodium Other anti-epileptic drugs such as effective treatment, poor symptom control were given propofol can control the onset of disease; 23 cases were cured, 3 patients died, 1 patient was discharged automatically. Conclusions Epileptic status is often caused by irregular medication in patients with cerebrovascular disease and idiopathic epilepsy. Encephalitis and traumatic brain injury are also common causes. Diazepam and phenobarbital sodium in the early episode have good therapeutic effect, Phenol can be used as the treatment of refractory epilepsy state of choice.