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系膜毛细血管肾小球肾炎伴有内皮下沉着物(Ⅰ型)不是一同源性疾病.Peters 等提出它可能是由于抗体不能清除抗原所引起,为一种免疫缺陷性综合症。本文报告1例系膜毛细血管性肾小球肾炎和免疫缺乏病人,而后者可能是病因。患者55岁,男性,有晕眩,血压170/100mmHg。尿常规有蛋白+。血尿素474 mg/100ml,血浆肌酐1.8mg%,总蛋白67g/L,白蛋白43g/L(均正常).蛋白尿1.8g/24 h 时尿 IgG 排泄0.13g/L。血 IgG7.55g/L,IgA0.35g/L和 IgM0.34g/L(正常值分别为9.5～16.5,0.90～4.50和0.65～2.0g/L)。血清 C_3、C_4和 CH_(50)均正常。2月后,患者发生流感样病后出现重度蛋白尿,肾活检发现是系膜毛细血
Mesangial capillary glomerulonephritis with endothelium (type I) is not a homologous disease, Peters et al suggest that it may be due to the antibody can not clear the antigen caused by an immunodeficiency syndrome. This article reports a case of mesangial capillary glomerulonephritis and immunodeficiency patients, the latter may be the cause. Patient 55 years old, male, with dizziness, blood pressure 170 / 100mmHg. Urine routine protein +. Blood urea 474 mg / 100ml, plasma creatinine 1.8mg%, total protein 67g / L, albumin 43g / L (all normal). Urinary albumin 1.8g / 24 h urinary IgG excretion 0.13g / L. Blood IgG7.55g / L, IgA0.35g / L and IgM0.34g / L (normal values were 9.5 ~ 16.5,0.90 ~ 4.50 and 0.65 ~ 2.0g / L). Serum C_3, C_4 and CH_ (50) were normal. After 2 months, severe proteinuria occurred in patients with influenza-like illness and renal biopsy was found to be mesangial capillary