论文部分内容阅读
本文探讨了维生素Ｅ（Ｖ＿Ｅ）对大鼠肝、肾和脑组织中过氧化脂质（ＬＰＯ）及谷胱甘肽过氧化物酶（ＧＳＨ－Ｐｘ）活性的影响。结果表明，５．０×１０￣（－５），１．０×１０￣（－４），２．０×１０￣（－４），４．０×１０（－４），６．０×１０￣（－５）Ｖ＿Ｅ，各剂量组大鼠肝、肾中ＬＰＯ含量均低于对照组，而脑组织中仅２．０×１０￣（－４）和６．０×１０￣（－４）组与对照组间有差异。ＧＳＨ－Ｐｘ活性只有２．０×１０￣（－４）和４．０×１０￣（－４）组与相应对照组有差异。结果提示：Ｖ＿Ｅ有降低ＬＰＯ的作用，但Ｖ＿Ｅ所致的ＧＳＨ－Ｐｘ活性升高与ＬＰＯ降低有一致性的原因有待进一步研究。
This article explored the effect of Vitamin E (VE) on lipid peroxidation (LPO) and glutathione peroxidase (GSH-Px) activity in rat liver, kidney and brain. The results showed that 5.0 × 10 -5, 1.0 × 10 -4, 2.0 × 10 -4, 4.0 × 10 -4, 6.0 × 10 ~ (-5) V_E, the content of LPO in the liver and kidney of each dose group was lower than that of the control group, while only 2.0 × 10 -4 and 6.0 × 10 -4 in the brain tissue There were differences between the groups and the control group. GSH-Px activity was only 2.0 × 10 -4 and 4.0 × 10 -4 groups with the corresponding control group differences. The results suggest that: V_E can reduce the role of LPO, but V_E-induced increased activity of GSH-Px and LPO reduce the consistency of the reasons to be further studied.