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N.Muirhead等通过对87-88年间22名肾移植术后妇女首次妊娠结果的分析,着重研究了妊娠期CsA的剂量,孕妇情况及CsA对胎儿的影响。 22名孕妇移植时平均年龄23.4±3.1岁,妊娠时年龄为26.3±3.7岁,术后至妊娠时间为1～75个月(34.5±24.5个月)。 12名孕妇接受单独CsA疗法或CsA+Aza+Pred或CsA+Pred疗法;10名接受单独Aza疗法或Aza+Pred法。妊娠时血清肌酐为68～265umol/L(Aza组106.4±32umol/L,CsA组128.4±59.2umol/L
N. Muirhead et al. Through the analysis of the results of the first pregnancy of 22 women after renal transplantation in 87-88 years, we focused on the dose of CsA during pregnancy, the condition of pregnant women and the effect of CsA on the fetus. Twenty-two pregnant women had an average age of 23.4 ± 3.1 years at transplantation, with a mean age of 26.3 ± 3.7 years and a postoperative period of 1 to 75 months (34.5 ± 24.5 months). Twelve pregnant women received CsA alone or CsA + Aza + Pred or CsA + Pred therapy; 10 received either Aza alone or Aza + Pred. Serum creatinine in pregnancy was 68 ~ 265umol / L (106.4 ± 32umol / L in Aza group, 128.4 ± 59.2umol / L in CsA group