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1 Results Our objective is two fold: we (ⅰ) aim at the development of novel patterning methodologies in order to (ⅱ) achieve control over the positioning and alignment of living cells.The patterning of the biointerfaces is carried out both at the micro-and nanometer scale and involve (bio)chemical as well as topographic patterns.The former are relatively easily obtained by patterning techniques adapted from (conventional) soft lithography,e.g.by means of micro-contact printing (μ-CP).The topographic patterns are fabricated by micromolding and nano-imprinting,to yield micro-and nano-sized structures,respectively.The imprinting of nanometer features into new,elastomeric biomaterials is a challenge and is achieved by tuning of the mechanical properties of the material and by the design of the mold.
1 Results Our objective is two fold: we (i) aim at the development of novel patterning methodologies in order to (ii) achieve control over the positioning and alignment of living cells. The patterning of the biointerfaces is carried out both at the micro- and nanometer scale and involve (bio) chemical as well as topographic patterns. The former are relatively easily obtained by patterning techniques adapted from conventional soft lithography, egby means of micro-contact printing (μ-CP). The topographic patterns are fabricated by micromolding and nano-imprinting, to yield micro-and nano-sized structures, respectively. imprometing of nanometer features into new, elastomeric biomaterials is a challenge and is achieved by tuning of the mechanical properties of the material and by the design of the mold.