病毒蛋白抗原表位的预测对于设计免疫原性多肽、新型疫苗分子及诊断试剂均有帮助.但是,既往的预测方法并不多,且至少存在以下两方面的缺陷:(1)既往方法均基于一般蛋白质的实验结果,因此,到目前为止还没有1种专用于病毒蛋白的表位预测方法;(2)80年代后期以来,多肽固相自动合成技术和Geysen氏pin ELISA技术在免疫学的广泛应用、模拟位 Prediction of epitopes of viral proteins is helpful for the design of immunogenic polypeptides, novel vaccine molecules and diagnostic reagents, however, there are not many previous prediction methods and at least the following two shortcomings: (1) Previous methods are based on Therefore, no specific epitope prediction method for viral proteins has been reported so far. (2) Since the late 1980s, peptide automated solid-phase synthesis and Geysen’s pin ELISA have been widely used in immunology Application, analog bit