论文部分内容阅读
本实验选用生育力正常成年雄性ＳＤ大鼠２５只，随机分为５组，行一侧输精管ＨＦＭＣ注射术，剂量为１０％ＨＦＭＣ２０μｌ（２ｍｇ），沉淀剂２０μｌ；另一侧输精管注射生理盐水４０μｌ对照，于注射时和注射后１、３、６、９和１２月分别测定双侧输精管ｐＨ值，其结果为注射ＨＦＭＣ侧输精管ｐＨ明显降低，为５．１８～５．８２，生理盐水对照侧为７．０４～７．６４，并随时间推移，注射ＨＦＭＣ侧输精管ｐＨ值逐渐升高，于术后１２月基本恢复与对照侧基本相同。提示：输精管注射ＨＦＭＣ后，能造成输精管内低ｐＨ值，改变了生殖系统内环境，影响精子功能，这可能是输精管内注射ＨＦＭＣ节育的机理之一。
In this experiment, 25 normal adult male SD rats of fertility were randomly divided into 5 groups, one side of the vas deferens HFMC injection, the dose of 10% HFMC20μl (2mg), precipitant 20μl; the other side of the vas deferens injected saline 40μl control , At the time of injection and 1, 3, 6, 9 and 12 months after injection, the bilateral vas deferens pH were measured respectively. The results showed that the vas deferens pH was significantly decreased from 5.18 to 5.82 on HFMC side, 7.04 ~ 7.64. With the passage of time, the pH value of the vas deferens on the HFMC side gradually increased, and the basic recovery after 12 months was basically the same as that on the control side. Hint: After injecting HFMC, the vas deferens can cause the low pH in the vas deferens, change the internal environment of the reproductive system and affect sperm function, which may be one of the mechanisms of sterilizing HFMC in vas deferens.