卡马西平(酰胺眯嗪carbamazepine,tegretol,CBZ)的化学结构与其它抗癫痫药不同,是亚氨芪(iminostilbine)的衍生物,与丙咪嗪结构相似。经临床试用对大发作、复合性部分发作及单纯部分性发作癫痫具有和苯妥英钠、苯巴比妥相等的疗效,且副作用小,尤适用于儿童、少年期及育龄妇女。国外报道CBZ血浓度与疗效、毒副作用有关,最适血浓度为3～12μg/ml。唾液中CBZ浓度与药物作用关系密切。本文对象为门诊和住院病人,表现为全身强直一 Carbamazepine (carbamazepine, tegretol, CBZ) chemical structure and other antiepileptic drugs is a derivative of iminostilbine, and imipramine structure similar. Clinical trials on the grand mal, combined partial seizures and simple partial seizures with phenytoin sodium, phenobarbital equal efficacy and side effects, especially suitable for children, adolescents and women of childbearing age. Foreign reports CBZ blood concentration and efficacy, side effects, the optimum blood concentration of 3 ~ 12μg / ml. The concentration of CBZ in saliva is closely related to the drug effect. This article is for outpatients and inpatients, manifested as systemic rigidity