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在成人皮肤与软组织的良性与恶性间叶性肿瘤中,呈脂原性分化者约占20％,为数量上最大的一组肿瘤。除较长时间以来已知的和业已定性的瘤种,如脂肪瘤、脂母细胞瘤、血管脂肪瘤、血管肌脂瘤、髓脂肪瘤、蛰伏脂瘤和梭形细胞及多形细胞脂肪瘤,以及各种不同类型的脂肪肉瘤等外,近年来又报道了一系列“新的”类型,与此有关的新知识,对于所遇脂肪瘤性肿瘤进行正确的临床病理和预后归类,具有重要意义。最近对其临床形态学、细胞发生学与分子病理学所见之相互关系的研究,对理解此组肿瘤的生物学很有帮助,并可据此(至少部分地)修订此类肿瘤的分类.
In benign and malignant mesenchymal tumors of adult skin and soft tissues, about 20% of the patients are differentiated by lipogenicity, which is the largest group of tumors. In addition to a long time known and well-characterized tumor types, such as lipoma, lipoblastoma, angiolipoma, angiomyolipomas, myelolipomas, politicoliticoma and spindle cells and pleomorphic lipomas As well as various types of liposarcoma, in recent years, a series of “new” types have been reported, and new knowledge related to this has been used to classify lipocarcinomas with the correct clinical pathology and prognosis. Significance. Recent studies on the relationship between clinical morphology, cytogenetics, and molecular pathology have been helpful in understanding the biology of this group of tumors, and can be used to (at least partially) revise the classification of such tumors.