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目的 :分析甲状腺淋巴瘤的类型及与临床的关系。方法 :采用 WHO2 0 0 0年淋巴肿瘤分类方案 ,光镜形态结合免疫组织化学结果对肿瘤进行分类 ,根据类型分为高度和低度恶性两组 ,结合临床和其他病理学所见进行分析。结果 :2 2例中 MZBL 6例和 FCL 1例 ;DL BCL1 5例。与低度恶性组比较高度恶性组更常见肿瘤浸润周围组织 ,临床分期较晚 (P<0 .0 5和 P<0 .0 1 )。肿瘤周围组织呈淋巴细胞性甲状腺炎常见 (1 7/ 2 2 ,77% )。结论 :甲状腺淋巴瘤的类型是异质性 ,有不同的临床和病理学表现 ,将甲状腺淋巴瘤统称为黏膜相关淋巴瘤易使临床医师发生误解
Objective: To analyze the type of thyroid lymphoma and its relationship with clinic. Methods: According to WHO classification of lymphoma in 2000, the tumor was classified by light microscope and immunohistochemistry. According to the classification, the tumors were divided into two groups according to their clinical and other pathological findings. Results: There were 6 cases of MZBL and 1 case of FCL in 22 cases, and 5 cases of DL BCL1. Compared with the low-grade group, the more malignant group was more common tumor infiltration of surrounding tissue, the clinical stage was late (P <0.05 and P <0.01). Peripheral tissue was lymphocytic thyroiditis common (1 7/2 2, 77%). CONCLUSIONS: The types of thyroid lymphoma are heterogeneous and have different clinical and pathological manifestations. It is easy for clinicians to misunderstand that the thyroid lymphoma is collectively referred to as mucosa-associated lymphoma