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目的探讨GDM(妊娠期糖尿病)孕妇的血清内脂素水平与糖代谢的关系。方法选取2014年2月~2015年2月来该院定期孕检的孕妇189例作为研究对象。其中初产妇162例,经产妇27例。根据孕妇于妊娠24~32周所作OGTT试验的血糖检测结果,将研究对象分成GDM组(89例)和NGT组(100例)。比较2个组患者的血清内脂素水平,考察其GDM发生的相关性。结果两个组在孕产次、体重指数、DM家族史、血清内脂素水平等指标的差异均有统计学意义(P<0.05)。其中,GDM孕妇的血清内脂素水平、血脂TG等显著升高。Logist多元回归分析发现,血清内脂素水平与GDM的发生存在正相关。结论 GDM孕妇的血清内脂素水平较NGT孕妇的显著升高。血清内脂素水平与GDM的发生存在正相关。
Objective To investigate the relationship between serum visfatin and glucose metabolism in pregnant women with GDM (gestational diabetes mellitus). Methods A total of 189 pregnant women who came to the hospital from February 2014 to February 2015 were selected as the study subjects. Among them, 162 cases of primipara and 27 cases of mothers. According to the blood glucose test results of pregnant women in the OGTT test conducted 24-24 weeks gestation, the subjects were divided into GDM group (n = 89) and NGT group (n = 100). Serum visfatin levels were compared between the two groups to investigate their association with GDM. Results The two groups had statistically significant differences in gestational age, body mass index, family history of DM and serum visfatin levels (P0.05). Among them, GDM pregnant women serum visfatin levels, blood lipids TG significantly increased. Logist multiple regression analysis found that serum visfatin levels and the occurrence of GDM is positively correlated. Conclusions Serum visfatin levels in GDM pregnant women are significantly higher than those in NGT pregnant women. Serum visfatin levels are positively correlated with the occurrence of GDM.