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粒细胞集落刺激因子(granulocyte colony-stimulating factor,G-CSF)是一种造血生长因子,可促进造血干细胞的增殖、分化及生存,在临床上广泛应用于治疗粒细胞减少症。近来越来越多的实验表明,G-CSF对神经系统具有明显的保护作用。文章阐述了G-CSF的神经保护作用机制。
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic growth factor that can promote the proliferation, differentiation and survival of hematopoietic stem cells and is widely used in the treatment of neutropenia. Recently, more and more experiments show that G-CSF has a significant protective effect on the nervous system. The article elaborates the neuroprotective mechanism of G-CSF.