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目的：研究胃病中P53和S—转移酶（GSTπ）表达及其临床意义。方法：应用免疫组织化学ABC方法检测5例正常胃组织和54例胃癌组织中P53蛋白和胎盘型谷胱甘肽的表达水平。结果：54例胃癌组织中P53和GSTπ阳性检出率分别为61．11％和68．52％。结论：检测P53和GSTπ有助于评估胃癌预后。
Objective: To study the expression of P53 and S-transferase (GSTπ) in gastric diseases and its clinical significance. Methods: The expression of P53 protein and placental glutathione in 5 normal gastric tissues and 54 gastric cancer tissues were detected by immunohistochemical ABC method. Results: The positive rates of P53 and GSTπ were 61.11% and 68.52% respectively in 54 cases of gastric cancer. Conclusion: Detection of P53 and GSTπ can help to evaluate the prognosis of gastric cancer.