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急性心肌梗塞(AMI)的溶栓疗法能最大限度地挽救濒死心肌,以防止梗塞扩大,缩小心肌缺血范围,降低病死率。我院从1994年8月—1995年10月对23例确诊为AMI的患者用尿激酶进行溶栓治疗,并辅以肝素钙和阿斯匹林.疗效满意,现报告如下.1 一般资料本组23例AMI患者,其中男19例,女4例,年龄28—69岁平均62.2岁,梗塞部位:广泛前壁3例,前壁4例,前间壁2例,下壁8例,下壁+前壁3例,下壁+正后壁2例,前壁+右室1例.2 治疗方法入院后阿斯匹林0.3g即刻顿服,同时将尿激酶50万U溶于0.85%的生理盐水40ml中静推,30min后重复一次,继以尿激酶10万U溶于0.85%生理盐水300ml中静滴,之后给肝素钙15000万U,每日一次,静点,共14天,辅以阿斯匹林0.3g/d,口服至出院.3 观察指标①胸痛程度.②心电图溶栓前作常规12导联,开始溶栓后30min,60min,90min,2h,4h,8h,12h,分别做心电图
Thrombolytic therapy for acute myocardial infarction (AMI) maximizes rescue of dying myocardium to prevent infarct enlargement, narrow myocardial ischemia, and reduce mortality. Thrombolytic therapy with urokinase in 23 patients diagnosed with AMI from August 1994 to October 1995 in our hospital was supplemented with heparin calcium and aspirin and the results were satisfactory.1 The general information 23 cases of AMI patients, including 19 males and 4 females, aged 28-69 years, an average of 62.2 years of age, infarct sites: extensive anterior wall in 3 cases, anterior wall in 4 cases, anterior wall in 2 cases, inferior wall in 8 cases, inferior wall + Anterior wall in 3 cases, inferior wall + is posterior wall in 2 cases, anterior wall + right ventricle in 1 case.2 treatment method after admission aspirin 0.3g immediate service, while urokinase 500000 U dissolved in 0.85% of the Saline 40ml static push, repeated 30min, followed by urokinase 100,000 U dissolved in 0.85% saline 300ml intravenous infusion of heparin 150,000 U, once daily, static point, a total of 14 days, supplemented To aspirin 0.3g / d, oral to discharge.3 Observation index ① degree of chest pain.② ECG before thrombolysis for routine 12 lead, thrombolysis began 30min, 60min, 90min, 2h, 4h, 8h, 12h, respectively Do electrocardiogram