青霉素是治疗革兰氏染色阳性球菌感染的有效抗生素之一,也是全国各地临床使用最广泛的一种抗生素。由于青霉素过敏反应时有发生,尤其是过敏性休克,严重者可以造成死亡。进一步了解青霉素过敏反应的发生原因,研究相应措施,以减少和防止青霉素过敏性休克发生,成为当前医疗工作中的一个重要课题。根据卫生部关于“提高抗生素质量”和“研究解决 Penicillin is one of the effective antibiotics for the treatment of Gram-positive cocci infections and is also one of the most widely used antibiotics in clinical practice throughout the country. Due to penicillin allergic reactions have occurred, especially in anaphylactic shock, severe cases can cause death. Further understanding of the causes of penicillin allergy, to study the corresponding measures to reduce and prevent the occurrence of anaphylactic shock with penicillin has become an important issue in the current medical work. According to the Ministry of Health on “improving the quality of antibiotics” and "research and solution