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应用７ＴＤ１／ＭＴＴ比色法对４０例卵巢上皮癌患者化疗前血清中白细胞介素－６（ｉｎｔｅｖｌｅｕｒｉｎ－６，ＩＬ－６）的生物活性进行了测定，以期探讨ＩＬ－６在化疗中的作用。结果：化疗ＩＬ－６高的患者对以卡铂为主的联合化疗不敏感。这一结果提示血清中ＩＬ－６可作为临床中制定合理化疗方案的参考指标。
The biological activity of interleukin-6 (IL-6) in serum of 40 patients with epithelial ovarian cancer before chemotherapy was determined by 7TD1 / MTT colorimetric assay in order to explore the role of IL-6 in chemotherapy. Results: Chemotherapy patients with high IL-6 were not sensitive to carboplatin-based combination chemotherapy. This result suggests that serum IL-6 can be used as a reference index for developing a rational chemotherapy regimen in clinic.