新生儿感染在新生儿疾病中占很大比例,特别是新生儿败血症病死率仍较高。新生儿感染无特异症状,诊断主要靠辅助检查,最可靠的诊断依据是血培养,但目前血培养阳性率不高,需时长,不适于早期诊断。急时相蛋白测定比血培养简单、迅速、较为可靠。我们测定了多种疾病新生儿81例血清C-反应蛋白(CRP)和前白蛋白(PA),其中部分动态观察了治疗前后的变化,以评价其临床意义。 Neonatal infection accounts for a large proportion of neonatal diseases, especially neonatal sepsis. Neonatal infection no specific symptoms, diagnosis mainly rely on auxiliary examination, the most reliable diagnosis is based on blood culture, but the current blood culture positive rate is not high, take a long time, not suitable for early diagnosis. Urgency protein measurement is simpler, faster and more reliable than blood culture. We measured 81 cases of newborns with a variety of diseases serum C-reactive protein (CRP) and prealbumin (PA), some of which were dynamically observed before and after treatment changes to evaluate its clinical significance.