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通过对CLa皮下避孕埋植剂长期使用者血液纤溶系统活性指标的测定认为,组织纤溶酶原激活物(t-pA)活性、纤溶酶原激活抑制物(PAI)活性、纤维蛋白、纤溶酶原都在正常值范围内,纤溶系统活性无异常改变。长期使用左旋18-甲基炔诺酮避孕埋植剂(平均每天释放量40μg左右)是安全的。
Through the determination of blood fibrinolytic activity of long-term users of CLa subcutaneous contraceptive implants, the activities of tissue plasminogen activator (t-pA), plasminogen activator inhibitor (PAI), fibrin, Plasminogen in the normal range, fibrinolytic system activity without abnormal changes. Long-term use of levonorgestrel contraceptive implants (average daily release of 40μg) is safe.