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目的 研究在急性心衰状态下动力性主动脉成形术对血液动力学的影响。方法 8条杂种犬 ,游离背阔肌 ,游离胸降主动脉 ;以背阔肌瓣包绕降主动脉 ;以异搏定诱导心衰 ;以骨骼肌刺激器刺激背阔肌瓣收缩。结果 心衰诱导满意 ,在主动脉成形术 (反搏 )后 ,与心衰时相比 ,舒张期平均压上升了 18 5 % ,心内膜下活力指数上升了 17 0 % ,冠脉流量增高了 2 6 8% ,肺毛细血管楔压下降了 19 4%。结论 在急性实验中 ,动力性降主动脉成形术可改善冠脉灌注和心肌氧供 ,改善心功能。该术式为充血性心衰病人提供了一种新的治疗途径。
Objective To study the hemodynamic effects of dynamic aortoplasty in acute heart failure. Methods Eight hybrid dogs with free latissimus dorsi and free descending thoracic aorta were inflated into the descending aorta by dorsal latissimus dorsi, heart failure was induced by intravenous injection of verapamil, and contraction of the latissimodal spine was stimulated by skeletal muscle stimulator. Results Heart failure was induced satisfactorily. After aortic dissection (EECP), mean diastolic pressure increased by 18.5%, sub-endothelial viability index increased by 17% and coronary flow increased compared with heart failure For 26.8%, pulmonary capillary wedge pressure decreased by 19.4%. Conclusions In an acute experiment, dynamic descending aortoplasty can improve coronary perfusion and myocardial oxygen supply and improve cardiac function. The procedure provides a new therapeutic approach for patients with congestive heart failure.