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目的:通过与单纯口服美多巴对照来评价100Hz电针治疗帕金森病对UPDRS评分的影响。方法:将60例确诊为帕金森病的患者随机分为治疗组和对照组,每组30例,同时服用美多巴,1次125mg,1日4次,治疗组在口服美多巴的基础上加用100Hz电针治疗。分别于治疗前、治疗后1个月、3个月和6个月回访时进行UPDRS评分,根据URDRS评分对其症状改善情况进行评价。结果:组内比较,治疗组在疗后1个月的评分差异无统计学意义(P>0.05),但在疗后3个月及6个月回访时均有统计学意义(P<0.05,P<0.01);对照组在疗后1个月、3个月及6个月回访时的差异均有统计学意义(P<0.01)。组间比较,治疗组和对照组在治疗1个月、3个月、6个月回访时组间评分比较均有统计学意义(P<0.01)。结论:100Hz电针加口服美多巴治疗帕金森病在UPDRS评分上明显优于对照组。
OBJECTIVE: To evaluate the effect of 100 Hz electroacupuncture on Parkinson’s disease on UPDRS score by comparing with oral meridional alone. Methods: Sixty patients diagnosed with Parkinson’s disease were randomly divided into treatment group and control group, with 30 cases in each group. Metroban, 125 mg once, and 4 times a day were used in the treatment group. On the increase with 100Hz EA treatment. UPDRS scores were collected before treatment, at 1 month, 3 months and 6 months after treatment, and their symptoms were evaluated according to URDRS score. Results: There was no significant difference in the scores of one month after treatment in the treatment group (P> 0.05), but there were significant differences at the three months and six months after the visit (P <0.05, P <0.01). There was significant difference in the control group at 1 month, 3 months and 6 months after the visit (P <0.01). Comparison between groups showed that there was significant difference between the treatment group and the control group in the 1 month, 3 months and 6 months follow-up visits (P <0.01). Conclusion: The treatment of Parkinson’s disease with 100Hz electroacupuncture plus omeprazole is superior to the control group in UPDRS score.