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作者对223例空洞型肺结核,痰结核菌阳性者,分别用乙胺丁醇(EMB)—异菸肼(INH),链霉素(SM)—乙胺丁醇—异菸肼两种治疗方法作对比观察,所有病例均系初治,均无肝、肾、颅神经疾患。结核菌对三种药物均敏感。随机分两组进行治疗,甲组(119例):EMB25毫克/公斤/日及INH450毫克/日,一次顿服,连续90天,然后将EMB改为15毫克/公斤/日,同时服Vit B_6 50毫克/日;乙组(104例):除上述治疗外,加用SMl.0/日,共90天。两组病例的年龄、性别,种族及病情均相仿。两组的非医疗原因失访率相仿;而由于药物的毒性或不能耐受性而失访者甲组10例(8.4％)。乙组
The authors of 223 cases of empty tuberculosis, sputum positive sputum TB patients were treated with ethambutol (EMB) - isoniazid (INH), streptomycin (SM) - ethambutol - isoniazid two treatment methods For comparative observation, all cases were naive, no liver, kidney, cranial nerve disorders. Mycobacterium tuberculosis is sensitive to all three drugs. The patients in group A (119 cases) were treated with EMB25 mg / kg / day and INH450 mg / day once daily for 90 consecutive days. Then, the EMB was changed to 15 mg / kg / day while taking Vit B_6 50 mg / day; Group B (104 cases): In addition to the above treatment, plus SMl.0 / day for a total of 90 days. The age, gender, race and condition of the two groups were similar. The two groups of non-medical reasons follow-up rate was similar; and because of the toxicity of drugs or intolerance and the loser A group of 10 patients (8.4%). Group B.