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妊娠中毒症的病因还不明确,在世界范围内本症仍是产妇死亡的第一位原因。来自胎盘的肾炎致病性糖蛋白:从人胎盘绒毛基底膜提取的糖蛋白同来自人类肾炎致病性糖蛋白的化学组成非常一致。其特征是糖的组成主要是葡萄糖酸,氨基酸的组成缺少胶原成分。利用 Ou-chterlony 法的凝胶内双扩散法,同人类致病性糖蛋白一样,形成单一的共同沉降线。在妊娠中毒症患者的尿中,用免疫学的方法证明存在 Con A 亲和性的肾炎致病性糖蛋白,明确提示来自胎盘的肾炎
The cause of gestosis is not yet clear, and the disease is still the first cause of maternal death in the world. Nephritis from Placenta Pathogenic Glycoproteins: Glycoproteins extracted from human placental villi basement membrane are highly consistent with the chemical composition from pathogenic glycoproteins of human nephritis. It is characterized by the composition of sugar is mainly gluconic acid, amino acid composition of the lack of collagen composition. In-gel double-diffusion method using the Ouchterlony method, like human pathogenic glycoproteins, forms a single co-sinking line. In the urine of patients with gestational toxicosis, nephritis-pathogenic glycoproteins with Con A affinity have been shown immunologically to clearly suggest nephritis from the placenta