论文部分内容阅读
目的:探讨可溶性髓系细胞触发受体-1(sTREM-1)表达水平与胸腔积液性质的相关性。方法:选择胸腔积液患者84例为研究对象(分为4组:结核性胸水24例;细菌性胸水22例;肿瘤性胸水16例;漏出液22例)。用酶联免疫吸附法(ELISA)分别检测患者胸水和血清中sTREM-1的表达水平,并分析比较。结果:4组患者胸水中,细菌性胸水组sTREM-1表达增高最显著,肿瘤性胸水组次之,漏出液胸水sTREM-1表达最低。4组患者血清中,细菌性胸水组sTREM-1的表达增高也最为显著,其他3组间差异无统计学意义。结论:sTREM-1表达水平对细菌性胸水、结核性胸水、肿瘤性胸水以及漏出液的鉴别诊断有较好价值,特别是对以胸膜细菌感染时胸水的诊断有较重要意义。
Objective: To investigate the correlation between the expression of sTREM-1 and pleural effusion in soluble myeloid cells. Methods: Eighty-four patients with pleural effusion were selected as study objects (divided into 4 groups: 24 cases of tuberculous pleural effusion, 22 cases of bacterial pleural effusion, 16 cases of tumorous pleural effusion and 22 cases of leakage fluid). The expression levels of sTREM-1 in pleural fluid and serum of patients were detected by enzyme-linked immunosorbent assay (ELISA) and analyzed. Results: The sTREM-1 expression in pleural effusion and bacterial pleural effusion in the 4 groups was the most significant. In the hydrothorax group, the expression of sTREM-1 in pleural effusion was the lowest. In the 4 groups of patients, the expression of sTREM-1 in bacterial pleural effusion group was the highest, and the difference was not statistically significant among the other 3 groups. Conclusion: The expression level of sTREM-1 is of great value in the differential diagnosis of bacterial pleural effusion, tuberculous pleural effusion, tumorous pleural effusion and leakage fluid, especially for the diagnosis of pleural effusion with pleural bacterial infection.