论文部分内容阅读
目的探讨无创正压通气治疗慢性阻塞性肺病(COPD)急性发作的临床价值。方法选取COPD急性发作患者120例,随机分为观察组、对照组,每组60例。观察组在常规治疗基础上行无创正压通气治疗,对照组在常规治疗基础上给予持续低流量吸氧治疗。比较两组治疗前、后动脉血气pH值、PaO2、PaCO2水平;对比两组住院时间、费用,以及气管插管及死亡情况。结果两组pH、PaO2、PaCO2值均较治疗前有所改善,且观察组改善情况优于对照组,差异有统计学意义(P均<0.05)。观察组住院时间和费用均低于对照组,差异有统计学意义(P均<0.05)。观察组实施气管插管9例(15.0%),死亡2例(3.3%);对照组分别为29例(48.3%)、8例(13.3%);两组比较,差异有统计学意义(P均<0.05)。结论无创正压通气治疗COPD急性发作的临床效果显著。
Objective To investigate the clinical value of non-invasive positive pressure ventilation in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods A total of 120 acute COPD patients were selected and randomly divided into observation group and control group, 60 cases in each group. The observation group was treated with non-invasive positive pressure ventilation on the basis of routine treatment, while the control group was given continuous low-flow oxygen therapy on the basis of routine treatment. The arterial blood gas pH, PaO2 and PaCO2 were compared between the two groups before and after treatment. The hospitalization time, cost, tracheal intubation and death were compared between the two groups. Results The values of pH, PaO2 and PaCO2 in both groups were improved compared with that before treatment, and the improvement in the observation group was better than that in the control group (P <0.05). The hospitalization time and cost in the observation group were lower than those in the control group, with significant difference (all P <0.05). There were 9 cases (15.0%) in the observation group and 2 death cases (3.3%) in the tracheal intubation group. The control group was 29 cases (48.3%) and 8 cases (13.3%) respectively. There was significant difference between the two groups All <0.05). Conclusion Noninvasive positive pressure ventilation in the treatment of acute exacerbation of COPD has a significant clinical effect.