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目的 :研究荆防挥发油的抗炎作用及对PGE2 的影响。方法 :对角叉菜胶致小鼠足跖肿胀、大鼠胸膜炎模型及大鼠弗氏完全佐剂所致关节炎肿胀的试验 ,并检测PGE2 的含量。结果 :荆防挥发油对多种炎症有显著的抑制作用 ,并能减少炎症介质PGE2 的含量。结论 :荆防挥发油有较好的抗炎效果 ,其抗炎机理与抑制PGE2 的产生有关。
Objective: To study the anti-inflammatory effects of volatile oil from Jingfen and its effect on PGE2. METHODS : Tests were conducted on carrageenan-induced paw swelling in rats, rat pleurisy models, and arthritis swelling caused by Freund’s complete adjuvant in rats. PGE2 levels were also measured. Results : Jingjing volatile oil had a significant inhibitory effect on many kinds of inflammation, and it could reduce the content of PGE2 in inflammation media. Conclusion : Jingjing volatile oil has good anti-inflammatory effect, and its anti-inflammatory mechanism is related to the inhibition of PGE2 production.