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1993～ 1996年间山东省有 71例临床诊断脊髓灰质炎病例 ,50例考虑与脊灰疫苗有关。按疫苗投放量统计相关病例发生率为 1/12 5万 ,首次服苗发生率为 1/2 1.88万 ,第二次服苗为 1/10 1.0 7万。用有病毒学支持的 31例分析 ,首次服苗发生率为 1/43.80万 ,第二次服苗为 1/164.2 5万。接触病例发生率为 1/10 4 4万 ,高于有关报道 ,其原因仍需进一步探讨。其它 2 1例仅临床上诊断为脊灰 ,但无病毒学支持。如何正确对脊灰临床病例分类是一个值得探讨的问题。
Between 1993 and 1996, 71 cases of polio were diagnosed in Shandong Province and 50 cases were related to polio vaccine. According to the vaccine dose statistics, the incidence rate of related cases was 1/12 50000, the incidence rate of the first service taking vaccine was 1/2188000 and the second serving service was 1/10 1.07 million. 31 cases with virological support analysis, the first incidence of service-taking vaccine 1 / 43.80 million, the second service was 1 / 164.2 50000. The incidence of contact cases was 1 104 million, higher than the relevant reports, the reasons still need to be further explored. The other 21 cases were clinically diagnosed with polio but no virologic support. How to correctly classify the clinical cases of polio is a problem worth exploring.