患儿,男,2岁,1987年1月28日以“全身荨麻诊,奇痒4天,便血1天”为主诉就诊。4天前,因接种冻干流脑多糖菌苗(卫制(82)汉(1)10号,卫生部武汉生物制品研究所,批号8615—3)后,全身皮肤发红,灼痒,继之出现风团,大小不一,以后逐渐增多,扩散全身,发热,即于当地医院肌肉注射地塞米松5mg,维丁胶性钙1支,同服扑尔敏、强的松、土霉素等2日,未能奏效,风团日渐增多,融合成片,一日来病情不断加重,出现腹痛、血便,速转我院求医,患儿第二胎足月顺产,生后发育良好,平素健康,一年前因接种同种菌苗后,全身起荨麻疹,经用抗组胺药物效果不佳,数日后逐渐消退,无其他药物过敏病史,家族中无同类病史。检查:体温36℃,脉搏140次,呼吸30次,发育 Children, male, 2 years old, January 28, 1987 to “systemic nettle diagnosis, itching 4 days, 1 day of stool” chief complaint. Four days ago, systemic skin redness and itching continued after inoculation of freeze-dried cerebrospinal fluid vaccine (Han (1) No. 10, Department of Health, Wuhan Institute of Biological Products, batch number 8615-3) The emergence of wind groups, different sizes, and gradually increased after the proliferation of systemic fever, that is, intramuscular injection of dexamethasone in the local hospital 5mg, a vinylbutyral calcium, with service chlorpheniramine, prednisone, oxytetracycline On the 2nd, did not work, the wind group is increasing, into a film, one day the condition continues to worsen, abdominal pain, bloody stools, speed transfer to our hospital for treatment, full-term follow-up of children with a second child after birth, good after birth, Usually healthy, a year ago due to inoculation of the same vaccine, the whole body from urticaria, with antihistamines ineffective, gradually faded after a few days, no other drug allergy history, family history of no similar. Check: body temperature 36 ℃, pulse 140 times, breathing 30 times, development