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本文采用间接免疫荧光法(单克隆抗体)检测了23例抗精子抗体阳性不育男性外周血的淋巴细胞亚群。结果表明,患者CD_3、CD_4和CD_8细胞百分率均明显低于正常生育男性,而CD_4/CD_8、B细胞和D_r细胞则明显增高。提示抗精子抗体阳性不育症存在免疫细胞数目异常,且T抑制细胞明显不足和B细胞的明显增加是此类患者发病的重要机制。
In this study, indirect immunofluorescence (monoclonal antibody) was used to detect the lymphocyte subsets in 23 cases of anti-sperm antibody-positive male peripheral blood. The results showed that the percentage of CD_3, CD_4 and CD_8 cells in patients was significantly lower than that in normal fertile men, while the percentage of CD_4 / CD_8, B cells and D_r cells were significantly increased. Tip anti-sperm antibody-positive infertility there is an abnormal number of immune cells, and T significantly inhibited the cells and B cells significantly increased the incidence of such an important mechanism of the disease.