1978～1986年,共收治小儿肾病综合征119例,对治疗效果不佳者26例作中段尿细菌培养,19例阳性,致病菌多为大肠杆菌。肾病合并泌尿系感染,大多缺乏典型症状,用激素治疗效果不佳。缓解病例多因尿路感染而复发,加抗菌素后达部分或完全缓解。故认为,难治性肾病及复发病例应常规做中段尿细菌培养。 From 1978 to 1986, a total of 119 cases of children with nephrotic syndrome were treated, 26 cases of poor treatment for urinary bacterial culture in the middle, 19 were positive, mostly E. coli. Nephropathy with urinary tract infection, most of the typical lack of symptoms, with hormonal treatment ineffective. More cases of remission due to urinary tract infection and recurrence, with antibiotics after partial or complete remission. Therefore, refractory renal disease and recurrent cases should be done routine urine bacterial culture.