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本文报道22例尿培养阳性的肾病综合征患儿,对激素和免疫抑制剂治疗效果不佳。经积极治疗尿路感染配合激素和免疫抑制剂治疗后,临床症状逐渐好转,尿蛋白转阴。根据患儿性别、年龄、肾病临床分型、尿路感染临床表现以及尿细胞学、免疫功能、尿培养细菌种类、药物敏感试验等加以分析,并就小儿肾病综合征易患尿路感染的原因加以讨论。由于合并尿路感染均缺乏典型尿路感染的症状,故建议中段尿培养应列为肾病的诊治常规。
This article reports 22 cases of urine culture-positive children with nephrotic syndrome, hormones and immunosuppressive agents ineffective treatment. After active treatment of urinary tract infection with hormones and immunosuppressive agents, the clinical symptoms gradually improved, urine protein turned negative. According to children’s gender, age, clinical classification of nephropathy, clinical manifestations of urinary tract infection and urinary cytology, immune function, bacterial culture of urine, drug sensitivity test analysis, and urinary tract infection in children with nephrotic syndrome causes Discuss it. Due to the lack of a typical urinary tract infection with urinary tract infection symptoms, it is recommended urinary culture should be listed as the diagnosis and treatment of renal disease routine.