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应用真彩色图象分析仪，定量观察因癌死亡的８１例尸检病例肺组织内的血小板巨核细胞（ＭＫｓ），其中４４例有肺转移，３７例无肺转移。观察发现，ＭＫｓ主要位于肺泡间隔毛细血管内，偶见于肺静脉和肺泡内，９８％以上的ＭＫｓ为裸核，少数有宽大伊红色胞浆。观察亦发现，有肺转移癌组（１３１ＭＫ／ｃｍ２肺组织）与无肺转移癌组（１２ＭＫ／ｃｍ２）和仅有肺外转移组（１２ＭＫ／ｃｍ２）ＭＫ的数量差别均有十分显著的统计学意义（Ｐ＜０．００１）。在肺转移癌组，肺内ＭＫ的多少与血栓和癌栓多少无关（Ｐ＞０．０５），但癌栓组（１２７ＭＫ／ｃｍ２）和癌栓＋癌结节组（１３０ＭＫ／ｃｍ２）的ＭＫ数量较单纯癌结节组（３７ＭＫ／ｃｍ２）明显增高。结果表明，肺组织内的ＭＫ在肺转移癌时明显增多，可能和肺部的癌栓能够刺激ＭＫ迁移到肺部有关。
A true color image analyzer was used to quantitatively observe platelet megakaryocytes (MKs) in the lung tissues of 81 autopsy cases that died of cancer, of which 44 cases had lung metastases and 37 cases had no lung metastases. It was observed that MKs were mainly located in the alveolar septal capillaries and occasionally in the pulmonary veins and alveoli. More than 98% of MKs were naked nucleus, and a few had large red cytoplasm. The observation also found that there was a statistically significant difference in the number of MK between lung metastatic carcinoma (131MK/cm2) and non-lung metastatic carcinoma (12MK/cm2) and extrapulmonary metastasis (12MK/cm2). Significance (P<0.001). In the lung metastatic carcinoma group, the amount of MK in the lung was not related to the number of thrombi and tumor thrombi (P>0.05), but the MK in the tumor thrombus group (127 MK/cm2) and the tumor thrombus + tumor nodule group (130 MK/cm2). The number was significantly higher than that of the simple nodule group (37 MK/cm2). The results showed that MK in the lung tissue increased significantly in metastatic lung cancers, which may be related to the migration of MK to the lungs by the tumor thrombus in the lungs.