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青霉素是临床上应用最广泛的抗生素。但容易发生过敏反应,严重时可出现过敏性休克,如不及时抢救,可危及生命。一、临床资料:急诊14例青霉素过敏反应的病人。病人曾用过青霉素,且注射前皮试结果仍为阴性。其中男5例,女9例,最大年龄70岁,最小18岁。肌肉或静脉注射完毕10分钟内出现过敏反应者6例,肌注未推完即出现反应的1例,静脉输入10分钟内出现的5例,发生在连续输液第三天的2例。仅出现荨麻疹,痒感,面色潮红的6例。除上述症状还有恶心呕吐,胸闷,呼吸困难,喉头水肿者5例,昏迷、血压下降等过敏性休克
Penicillin is the most widely used antibiotics in clinical practice. But prone to allergic reactions, severe allergic shock may occur, if not rescued, can be life-threatening. First, the clinical data: emergency 14 cases of penicillin allergic reaction in patients. The patient had ever used penicillin and the skin test results were still negative before injection. There were 5 males and 9 females, the oldest was 70 years old and the youngest was 18 years old. 6 cases had anaphylactic reaction within 10 minutes after intramuscular or intravenous injection, 1 case showed intramuscular injection without reaction, 5 cases occurred within 10 minutes after intravenous infusion, and 2 cases occurred on the third day of continuous infusion. Only appeared urticaria, itching, flushing in 6 cases. In addition to the above symptoms are nausea and vomiting, chest tightness, difficulty breathing, laryngeal edema in 5 cases, coma, decreased blood pressure and other anaphylactic shock