自从1976年哌唑嗪(Prazosine),应用于临床以来,已在高血压、心衰、冠心、嗜铬细胞瘤等的治疗方面,取得显著疗效。长期应用,突然停药,可使病情恶化,甚至造成死亡。谓之“停药综合征”。现就我们所遇三例,报告如下。例一,男,72岁,因反复咳喘、心悸、浮肿三年加重四天,于85年11月23日入院。患者于81年9月发生“急性前壁广泛心肌梗塞”,自此每当生气、劳累、受凉、天气剧变时,即咳嗽吐泡沫性白痰,心悸、呼吸困难、不能平卧、浮肿,曾多次住院,诊断心 Prazosine has been used clinically since 1976 and has achieved remarkable results in the treatment of hypertension, heart failure, coronary heart disease and pheochromocytoma. Long-term application, sudden withdrawal, can make the condition worse, and even cause death. That the “withdrawal syndrome.” Now we encounter three cases, the report is as follows. Example 1, male, 72 years old, due to repeated cough, heart palpitations, edema aggravated three years for three years, on November 23, 85 admission. Patients in September 81, “acute anterior wall widespread myocardial infarction,” Whenever angry, tired, cold, the weather deteriorated, the cough spit foam white sputum, palpitations, difficulty breathing, can not lie down, edema, had Repeatedly hospitalized, diagnosed heart