喹唑啉衍生物具有广泛的农药生物活性,如抗细菌、抗真菌、杀虫、除草、抗病毒及杀螨等,近年来受到越来越多的关注。将不同药效团引入到喹唑啉骨架中,经结构修饰后能合成一系列具有农药生物活性的新型喹唑啉衍生物。本文综述了2000年以来喹唑啉衍生物的合成及农药活性研究进展,旨在为喹唑啉结构的修饰改造提供参考。 Quinazoline derivatives have a wide range of biological activity of pesticides, such as antibacterial, antifungal, insecticidal, herbicidal, antiviral and acaricidal and so on, in recent years by more and more attention. Different pharmacophores were introduced into the quinazoline skeleton, and a series of novel quinazoline derivatives with pesticidal bioactivity were synthesized after structural modification. This review summarizes the progress of quinazoline derivatives synthesis and pesticide activity since 2000, aiming to provide references for the modification and modification of quinazoline structures.