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[目的]探讨冷藏灌注液在白内障超声乳化术中应用的可行性及临床疗效。[方法]选择白内障超声乳化术184例，根据灌注液的温度分为常温组（A组）92例（138眼）和冷藏液组（B组）92例（129眼），比较两组患者术中、术后角膜灼伤和角膜水肿情况。[结果]A组术中角膜不同程度灼伤患者5例（3．62％）显著高于B组（0例），A组术后d1角膜水肿者70眼（50．7％）显著高于B组23眼（17．5％），其差异有显著性（ P ＜0．05）。[结论]在白内障超声乳化术中使用冷藏灌注液能有效降低超声乳化头产热所致的高温，防止角膜的灼伤和减轻角膜内皮的损伤。“,”[Objective] To explore the feasibility and clinical efficacy of refrigerated perfusion fluid in phacoemulsifi-cation .[Methods]Totally 184 cases of phacoemulsification were chosen .According to the temperature of perfusion fluid , all cases were divided into normothermia group (group A ,n=92 ,138 eyes) and refrigerated liquid group (group B ,n=92 ,129 eyes) .Corneal burns and edema of patients in two groups were compared between intraoperation and postopera-tion .[Results]Different degrees of corneal burns were found in 5 cases of group A(3 .62% ) ,which was markedly higher than that of group B(0% ) .Corneal edema was found in 70 eyes of group A on d1 after operation(50 .7% ) ,which was markedly higher than that of group B (17 .5% ) ,and there was significant difference ( P<0 .05) .[Conclusion]In phacoe-mulsification ,the refrigerated perfusion fluid can effectively reduce the heat caused by ultra-high temperature nipple ,pre-vent corneal burns and reduce corneal endothelial damage .