影响先天性膈疝(CDH)预后的主要因素是肺发育不良和肺动脉高压,目前各种出生后治疗手段均不能直接、立即改变已经存在的肺发育不良状态,故无法从根本上改善严重CDH的预后。宫内诊断并适时进行干预可能成为CDH有效的一种治疗手段。文章介绍了超声及MR I检查在CDH宫内诊断与肺发育程度评估方面的应用、以胎儿镜下胎儿气管球囊封堵术为重点的宫内干预及子宫外产时处理技术的应用。 The main factors that affect the prognosis of congenital diaphragmatic hernia (CDH) are pulmonary dysplasia and pulmonary hypertension. At present, all kinds of post-natal treatment methods can not directly and immediately change the existing state of lung dysplasia, so it can not fundamentally improve the prognosis of severe CDH . Intrauterine diagnosis and timely intervention may be a CDH effective treatment. This article introduces the application of ultrasound and MR I in the diagnosis of intrauterine diagnosis of CDH and the degree of lung development. The intrauterine intervention with intrauterine fetal FTCG and the technique of extrauterine delivery are introduced.