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  5. Redox and pH-responsive PAMAM-SS-PEG conjugates incorporated with DOX for efficient intracellular dr

Redox and pH-responsive PAMAM-SS-PEG conjugates incorporated with DOX for efficient intracellular dr

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：y51211
【摘 要】
：
Nanocarriers with low toxicity, high stability, long circulation in blood and triggered drug release at target sites are extremely needed for cancer therapy.In this study, different molar ratios of po
【作 者】
：
Wen Hu Liang Cheng Lifang Cheng Qifu Lei Ziyang Hu M ing xu Lipeng Qiu Dawei Chen 
【机 构】
：
Department of Pharmaceutics,College of Pharmaceutical Sciences,Soochow University,Suzhou 215123,Chin
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
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Nanocarriers with low toxicity, high stability, long circulation in blood and triggered drug release at target sites are extremely needed for cancer therapy.In this study, different molar ratios of poly (ethylene glycol) (PEG) were conjugated to poly (amidoamine) dendrimer (PAMAM) by cleavable disulfide bonds, yielding redox and pH dual-responsive nanocarriers (PSSP).
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