sirolimus相关论文
Sirolimus combined with oseltamivir and corticosteroid treatment for a puerpera with severe pneumoni
Severe pneumonia in patients infected with the 2009 pandemic H1N1 (pH1N1) virus was partially attributed to excessive im......
Objective Pulmonary lymphangioleiomyomatosis (PLAM) is a rare disease occurring exclusively in women, whose diagnosis is......
The remission of renal injury in tacrolimus to sirolimus conversion renal transplant recipients is d
Background: Conversion from tacrolimus to sirolimus-based immunosuppression is associated with improved renal function a......
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Sirolimus solid self-microemulsifying pellets:formulation development,characterization and bioavaila
To enhance the dissolution and oral absorption of water insoluble drug sirolimus (SRL),self-microemulsifying pellets of ......
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Individualized Immunosuppressive Protocol of Liver Transplant Recipient Should be Made Based on Sple
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Gender difference on five-year outcomes of EXCEL biodegradable polymer-coated sirolimus-eluting sten
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One-year clinical outcomes of Chinese sirolimus-eluting stent in the treatment of unselected patient
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Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent reste
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BACKGROUND Blue rubber bleb naevus syndrome(BRBNS)is a rare disease that usually presents with multiple venous malformat......
A simple and sensitive LC-MSMSmethod for simultaneous determination of temsirolimus and its major me
A simple,fast and sensitive LC-MS/MS method was developed and validated for the simultaneous determination of the co......
Objective Sirolimus is an immunosuppressive drug with a narrow therapeutic range and wide inter- individual variation in......
目的探讨西罗莫司治疗难治性免疫性血细胞减少症的疗效。方法回顾性分析郑州大学第一附属医院2017年10月至2018年10月收治的6例难......
比较西罗莫司(sirolimus)洗脱支架与金属裸支架对小腿动脉狭窄的治疗效果。50例病人随机分为两组:①使用洗脱支架;②使用金属裸支......
目的 卡波西样血管内皮瘤（kaposiform hemangioendothelioma，KHE）属于血管性肿瘤的特殊类型，临床上易伴发Kasabach-Merritt现象（kasabac......
目的分析卡波西样淋巴管瘤病(kaposiform lymphangiomatosis，KLA)的疾病特征并介绍西罗莫司治疗该病的初步经验，以提高医生对该病的......
Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular ca
AIM: To report a retrospective analysis of preliminary results of 36 patients who received sirolimus (SRL, Rapamune(R), ......
1例54岁男性患者因急性心肌梗死先后2次行经皮冠状动脉介入治疗(PCI)。第1次PCI植入西罗莫司洗脱支架5枚，术后5周患者出现胸闷、憋......
1例8月龄女婴确诊为卡波西样血管内皮瘤(KHE)，给予普萘洛尔2 mg口服、2次/d，泼尼松7.5 mg口服、1次/d。因疗效不佳，停用普萘洛尔和泼......
目的 探讨以西罗莫司为主的联合免疫治疗方案(SCTR)对肝癌肝移植受者体内调节性T细胞(Treg)和效应性T细胞表达的影响.方法 对2010......
目的 探讨肾移植受者同时服用西罗莫司与低剂量环孢素A的免疫抑制方案的可行性及价值.方法 研究分为实验组和对照组,每组肾移植受......
目的 观察雷帕霉素与紫杉醇药物洗脱支架(DES)置入后再狭窄率、支架内血栓形成及4年临床结果.方法 回顾性分析2003年1-10月连续237......
目的 探讨肝癌肝移植受者术后采用以西罗莫司联合两剂激素为主的免疫抑制方案的安全性和有效性.方法 2004年3月至2006年10月间,共......
Objective:To investigate the clinical application of sirolimus (SRL) in renal post-transplant which included sirolimus i......
Sirolimusasprimaryimmunosuppressantfor calcineurininhibitor-relatedrenalinsufifciency after liver tr
BACKGROUND:Calcineurin inhibitor-related renal toxicity affects patient and graft survival in transplant recipients. Thi......
目的探讨西罗莫司诱导K562细胞γ珠蛋白基因表达的作用机制。方法终浓度10 nmol·L-1西罗莫司处理K562细胞3 d,同时设立阳性药物(......
目的:比较紫杉醇洗脱支架(PES)与西罗莫司洗脱支架(SES)在糖尿病患者冠状动脉介入治疗中的有效性和安全性。方法:通过Medline、EMB......
目的:为了促进难溶性药物西罗莫司(sirolimus,SRL)的口服吸收,制备西罗莫司自微乳化微丸(SRL-SMEDDS pellets,SSP),并对其进行体内......
1.研究背景: 目前非霍奇金氏淋巴瘤(Non—Hodgkins Lymphoma，NHL)的发病率在全球范围内呈逐渐上升的趋势，在中国，NHL发病率亦有上......
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目的 探讨国产外周动脉雷帕霉素.肝素洗脱支架(SHES)的物理性能,生物相容性和体内外药代动力学特性,以及其对再狭窄的抑制作用.方......
目的:对西罗莫司(SRL)滴丸在大鼠体内的生物利用度进行研究。方法:以PEG6000为基质,采用溶剂-熔融法制备SRL滴丸;以SRL市售片为参......
目的:探讨糖尿病大鼠肾组织肿瘤坏死因子α(TNF-α)、核转录因子- κB (NF-κB)对肾组织细胞凋亡的诱导以及雷帕霉素干预的作用.方......
目的 评价国产雷帕霉素-聚丙交酯乙交酯(PLGA)外周动脉洗脱支架药膜性能及其药物释放特点.方法 采用自制PLGA与雷帕霉素制成雷帕霉......
目的 探讨西罗萸司(SRL)对人肝癌裸鼠肝脏移植瘤生长的影响.方法 建立人肝癌裸鼠肝脏移植瘤模型,使用SRL、他克莫司(FK506)进行干......
目的探讨雷帕霉素治疗结节性硬化症(TSC)合并心脏横纹肌瘤的临床效果及安全性。方法收集自2011年9月至2015年11月在解放军总医院儿......
Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent reste
With widespread performance of coronary artery stenting, the number of in-stent restenosis (ISR) has increased in recen......
One-year clinical outcomes of Chinese sirolimus-eluting stent in the treatment of unselected patient
The application of drug-eluting stent (DES), either sirolimus-eluting stent (Cypher, Cordis, USA) or paclitaxel-eluting......
Sirolimus-eluting cobalt alloyed stents in treating patients with coronary artery disease: six-month
Background The emergence of drug-eluting stents (DES) has dramatically reduced the incidence of in-stent restenosis.This......
Inflammation inhibitory effects of sirolimus and paclitaxel-eluting stents on interleukin-1β-induced
Background Coronary artery in-stent restenosis (ISR) and late stent thrombosis remain as important complications of sten......
Background Docetaxel (DOC) therapy is well tolerated and shows high response rates in patients with hormone refractory p......
Gender difference on five-year outcomes of EXCEL biodegradable polymer-coated sirolimus-eluting sten
Background The gender difference on long-term outcome in unselected patients after percutaneous coronary intervention (P......
Efficacy and safety of FIREHAWK(R) abluminal groove filled biodegradable polymer sirolimus-eluting s
Background Previous studies indicated that long coronary lesions are one of the key predictors of drug-eluting stent (DE......
Background:The phosphorylation ofp70S6 kinase (p70S6K) represents an important target for sensitive detection on pharmac......
Individualized Immunosuppressive Protocol of Liver Transplant Recipient Should be Made Based on Sple
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目的：评价年龄因素对选择性冠状动脉内置入雷帕霉素洗脱支架（ DES ）的远期疗效的影响。方法对成功置入DES的316例男性冠心病患者进行......
