pemetrexed相关论文
目的:探讨血清miRNA-126（miR-126）、miRNA-449a（miR-449a）的表达水平对培美曲塞联合顺铂治疗非小细胞肺癌（NSCLC）的效果和预后的评估作用......
Host-guest inclusion for enhancing anticancer activity of pemetrexed against lung carcinoma and decr
Advanced chemotherapy strategies are in urgent demand for improving anticancer efficacy.Herein,a water-soluble pillar[6]......
EarlyDetectionofPemetrexed-inducedInhibitionofThymidylate SynthaseinNon-SmallCellLungCan
Purpose:Inhibitionofthymidylatesynthase(TS)resultsinatransientburstor“flare”inDNAthymidinesalvagepathway activitymeasu......
Upregulation of FRα by Decitabine Sensitizes Acquired Radioresistant Lung Adenocarcinoma Cells to Pe
Objective The radiation resistance of lung adenocarcinoma remains a major therapeutic problem,and chemotherapy drugs are......
ThevalueofPemetrexedforthetreatmentofbrainmetastasesfromnon-smallcelllungcancer(NSCLC)
目的 Theincidenceofbrainmetastases(BM)fromnon-small-lungcancer(NSCLC)isincreasingasaresultofadvancedimagingtechniquesfor......
Superior antimetastatic effect of pemetrexed-loaded PEG-Peptide-PCL nanoparticles in a mouse metasta
Using nanoparticle delivery for anticancer therapy is a potential new drug modality.We developed a novel pemetrexed-load......
Randomized trial of gefitinib with and without pemetrexed as first-line therapy in East-Asian patien
目的： Pemetrexed (P) is the standard of care for non-squamous non-small cell lung cancer (NS NSCLC)， whereas epidermal gro......
Potential role of pemetrexed in metastatic breast cancer patients pretreated with anthracycline or t
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目的比较首批城市药品集中带量采购中标的四川汇宇制药股份有限公司生产的培美曲塞（仿制药）与Eli Lilly Nederland B.V.生产的培美曲......
The inhibition of the pemetrexed-activated, MAPK pathway via sorafenib is involved in the synergisti
Background The effect of combined administration of multi-targeted receptor tyrosine kinase (RTK) inhibitor (sorafen......
目的评价培美曲塞联合奈达铂治疗一线治疗失败的尿路上皮癌患者的疗效与安全性。方法回顾性分析2016年3月至2018年2月采用GC方案(......
目的：培美曲塞已被确定为晚期非小细胞肺癌（非鳞癌）的标准用药之一。本研究旨在探讨培美曲塞治疗非小细胞肺癌无症状脑转移的近期疗效......
目的观察培美曲塞单药或联合铂类治疗一线失败的晚期非鳞非小细胞肺癌(NSCLC)的临床效果。方法经病理学或细胞学确诊的34例晚期非......
Background and objective Pemetrexed have been approved for the treatment of patients affected by advanced non-small cell......
目的研究培美曲塞联合顺铂(PP方案)一线治疗及培美曲塞单药序贯维持方案对老年非小细胞肺癌(NSCLC)患者的临床疗效及安全性。方法......
目的探讨胸腺肽α1联合培美曲塞治疗局部晚期非小细胞肺癌的临床治疗效果。方法选取2012年3月至2017年3月孝义市人民医院呼吸科收......
1例68岁男性肺癌患者接受培美曲塞二钠和贝伐珠单抗联合治疗，静脉滴注注射用培美曲塞二钠结束后约20 min，患者突发胸闷气急、大汗淋......
1例70岁女性患者因转移性非小细胞肺癌接受培美曲塞联合顺铂方案化疗，化疗2个周期后，肺癌部分缓解，但出现Ⅱ级白细胞计数(WBC)减少和......
First-line pemetrexed-platinum doublet chemotherapy with or without bevacizumab in non-squamous non-
Objective:To evaluate the efficacy and safety profile of first-line bevacizumab (Bev)-containing pemetrexed-platinum che......
Antitumor and vascular effects of apatinib combined with chemotherapy in mice with non-small-cell lu
Objective The aim of this study was to investigate the antitumor and vascular effects of apatinib use combined with chem......
目的 观察培美曲塞(Pemetrexed,PEM)联合卡铂(carboplatin,CBP)治疗老年晚期非小细胞肺癌(NSCLC)的有效性和毒副反应.方法 49例老......
目的比较培美曲塞(PEM)联合顺铂(DDP)与多西他赛(DOC)联合顺铂(DDP)治疗晚期肺腺癌的临床疗效及不良反应。方法将45例晚期肺腺癌（Ⅲ......
目的探讨培美曲塞联合顺铂二线治疗治疗晚期卵巢癌的疗效以及不良反应。方法经病理学或细胞学确诊的晚期卵巢癌患者41例,中位年龄4......
目的探讨培美曲赛联合顺铂治疗晚期非小细胞肺癌的疗效及毒副反应。方法选择70例患者,分为PEM组、GP组各35例,分别接受培美曲赛联......
目的 探讨培美曲塞方案用于非鳞非小细胞肺癌术后辅助化疗的疗效及毒副反应.方法 收集肺癌根治手术后病理证实的分期为ⅠA-ⅢB期的......
Pemetrexed monotherapy versus pemetrexed plus platinum combination as second-line treatment for adva
Background Pemetrexed is a novel folic acid antagonist with multiple targets, which has been widely used in the treatmen......
Survival without common toxicity criteria grade 3/4 toxicity following second-line treatment with pe
Background The efficacy of pemetrexed in the second-line treatment of Chinese patients with advanced non-small cell lung......
Pemetrexed Monotherapy and Pemetrexed Plus Platinum Combination Therapy as Non-First-Line Treatments
OBJECTIVE Data on the efficacy profiles of pemetrexed monotherapy and pemetrexed plus platinum combination therapy in th......
目的探讨培美曲塞联合奈达铂二线治疗对肺腺癌患者近期疗效及远期生存率的影响。方法将2012年5月-2015年6月延安大学附属医院收治......
目的观察培美曲塞(PEM)联合顺铂(DDP)治疗晚期肺腺癌的临床疗效及不良反应。方法将52例晚期肺腺癌患者随机分为观察组和对照组各26......
目的 比较晚期非小细胞肺癌(NSCLC)患者一线化疗获益后继续行培美曲塞维持治疗与疾病进展后延迟治疗的疗效.方法 选取我院经一线含......
目的 探讨培美曲塞二线治疗晚期非小细胞肺癌(NSCLC)的临床疗效.方法 一线含铂方案化疗后复发的晚期NSCLC患者50例,使用培美曲塞(5......
目的探讨培美曲塞联合顺铂(PC方案)一线治疗晚期肺腺癌的疗效。方法初治晚期肺腺癌患者100例均分为两组:A组接受PC方案治疗,B组采......
目的探讨培美曲塞联合顺铂对人结肠癌细胞SW480增殖和凋亡的影响。方法 SW480细胞单用培美曲塞(A组)、顺铂(B组)或二药联用(AB组)......
目的评价培美曲塞联合顺铂(PC方案)和多西他塞联合顺铂(DP方案)治疗非小细胞肺癌(NSCLC)的疗效。方法 78例NSCLC患者随机分为两组:......
Objective:The aim of our study was to observe the efficacy and toxicity of 50 cases of advanced non-small cell lung canc......
Toxic epidermal necrolysis related to AP (pemetrexed plus cisplatin) and gefitinib combination thera
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Effects of endostatin combined with pemetrexed and cisplatin on the levels of TNF-α, NSE, CEA, CA199
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
【摘要】 目的 观察培美曲塞治疗老年晚期非小细胞肺癌的疗效和毒副反应，探寻相对应的护理方法。方法 通过对32例老年晚期非小细胞......
[目的]观察培美曲赛联合铂类(顺铂、卡铂或奈达铂)一线治疗ⅢB/Ⅳ期肺腺癌患者的近期疗效及毒副反应.[方法]20例初治ⅢB/Ⅳ期肺腺......
目的观察不同浓度培美曲塞作用于外周T细胞淋巴瘤细胞Jurkat及Hut-78细胞后的不同时间的外周T细胞淋巴瘤的细胞生长抑制情况,并探......
Clinical Study of Pemetrexed as the First-line Treatment in Elderly Patients with Advanced Non-squam
Objective:To evaluate the efifcacy and adverse reactions of pemetrexed as the ifrst-line treatment in elderly patients w......
目的：探讨培美曲塞单药治疗老年晚期非小细胞肺癌(NSCLC)的疗效及不良反应。方法：21例经病理学确诊的晚期NSCLC接受培美曲塞单药化疗......
目的评价放疗联合培美曲赛加顺铂（PC方案）同期治疗无法手术局部晚期肺腺癌远期疗效和毒副反应，探讨该治疗模式的疗效和安全性。方法回......
目的探讨培美曲赛联合奈达铂治疗晚期肺腺癌的疗效及毒副作用。方法收集48例经病理组织学或细胞学确诊的晚期肺腺癌患者，接受培美曲......
目的：探讨培美曲塞联合卡铂治疗辅助化疗失败的转移性乳腺癌的疗效和不良反应。方法：收集已接受过辅助化疗的转移性乳腺癌患者45例，给......
Objective:The aim of our study was to observe the efficacy and toxicity of 50 cases of advanced non-small cell lung canc......
