organoid相关论文
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Cancers of the digestive system(DS),including esophageal,gastric,colorectal,liver,and pancreatic can-cers,have a high in......
The neuromuscular junction (NMJ),a peripheral synaptic connection between motoneurons and skeletal muscle fibers,control......
研究目的:胰腺癌仍然是目前医学界最具有挑战性的疾病,特别是那些失去外科手术机会或者术后复发的晚期胰腺癌患者,长期生存率依然......
miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signali
Objective Emerging evidence suggested that miRNAs can function as oncogenes or tumor suppressors by regulating downstrea......
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Owing to the paucity of donor organs and their acute rejection by the immune system after transplantation,advanced organ......
Limitations of monolayer culture conditions have motivated scientists to explore new models that can recapitulate the ar......
Owing to the paucity of donor organs and their acute rejection by the immune system after transplan-tation,advanced orga......
Three-dimensional(3D)organoids derived from pluripotent or adult tissue stem cells seem to possess excellent potential f......
Recent developments in organoid culture technologies have made it possible to closely recapitulate intrinsic characteris......
For centuries, attempts have been continuously made to artificially reconstitute counterparts of in vivo organs from the......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Time-restricted feeding downregulates cholesterol biosynthesis program via RORγ-mediated chromatin m
Background: Time-restricted feeding(TRF) is a dieting strategy based on nutrients availability and diurnal rhythm,shown ......
类器官是由正常组织或肿瘤的特异性干细胞,在体外三维培养条件下,形成的三维体外细胞结构,具有自我组织形成类似于原始组织的"微型......
类器官作为新一代临床前肿瘤模型,其建立对于揭示肿瘤生物学特性及探索对肿瘤患者有效的治疗方法具有重要意义。前列腺来源的类器官......
Long-term culture-induced phenotypic difference and efficient cryopreservation of small intestinal o
AIM To investigate a suitable long-term culture system and optimal cryopreservation of intestinal organoid to improve or......
Accumulation of lactate in tumor has been linked to poor prognosis of oral squamous cell carcinoma (OSCC), but the under......
Intestinal epithelial stem cells (IESCs) are one of the most rapidly self‐renewing and proliferating adult stem cells. ......
类器官是一种新型体外研究模型,由干细胞或肿瘤细胞在三维培养条件下自我组装而成。它能够高度模拟原位组织的生理结构和功能,经长......
Stem cells have moved from lab to bedside, and many initial studies showed promising results. Therefore big companies ar......
BACKGROUND Liver organoids have recently been applied as models for liver disease and drug screening,especially when com......
Despite a continuing increase in the number of patients suffering from chronic kidney disease,currently available treatm......