hepatocytes相关论文
Defects in mitochondria are responsible for various ge-netic and acquired diseases. Mitochondrial transplantation, a met......
Chemical characters and protective effect of Baqi Lingmao formula(巴芪灵猫方) on experimental liver injur
OBJECTIVE:To investigate the chemical characters of water-extract of Baqi Lingmao formula(巴芪灵猫方,BQLM formula) and i......
Assessment of SENP3-interacting proteins in hepatocytes treated with diethylnitrosamine by BiolD ass
SUMOylation of proteins regulates cell behaviors and is reversibly removed by small ubiquitin-like modifier(SUMO)-specif......
NEFA induce dairy cows hepatocytes apoptosis through mitochondrial-mediated ROS-JNK/ERK signaling pa
Elevated plasma nonesterified fatty acids (NEFA) and hepatocytes damage are features of ketosis in dairy cows.Oxidative ......
Non-esterified fatty acids induce expression and secretion of angiopoietin-like protein 4 in calf he
[Background/Aims]An elevated concentration of plasma non-esterified fatty acids (NEFA) is an important indicator of nega......
Insulin suppresses the AMPK signaling pathway to regulate lipid metabolism in hepatocytes of dairy c
Dairy cows with type Ⅱ ketosis displayed hepatic fat accumulation and hyperinsulinemia, while the underlying mechanism ......
Herbicide acetochlor after application enters both surface and underground waters, so that the equilibrated acetochlor c......
Autophagy dysfunction is considered as a potential toxic mechanism of nanomaterials1.Silica nanoparticles(SiNPs) induced......
Substrate Stiffness and Topology Regulates Differentiation of Embryonic Stem Cells to Functional Hep
Background&Aims:Hepatocytes differentiated from human embryonic stem cells(hESCs)have the potential to overcome the shor......
Wogonin (5,7-dihydroxy-8-methoxyflavone, WG, Fig.1) is an attractive candidate for the development of new anti-cancer dr......
P13.EFFECT OF FLUORIDE ON ACTIVITIES OF ENZYME AND ULTRASTRUCTURE IN PRIMARY CULTURED RAT HEPATOCYTE
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AMPK signaling pathway and activation of SREBP1 in the promoted hepatic lipid accumulation by SSRI a
Fluoxetine (FLX),a typical drug belonging to the category of selective serotonin reuptake inhibitors (SSRI),is the most ......
Macrophage Migration Inhibitor Factor Upregulates MCP-1 Expression in an Autocrine Manner in Hepatoc
Macrophage migration inhibitor factor (MIF),a multipotent innate immune mediator,is an upstream component of the inflamm......
ESTABLISHMENT OF CRYOPRESERVATION AND RETRIEVE SYSTEM OPTIMIZED FOR HUMAN EMBRYONIC STEM CELLS-DERIV
The liver is a multifunctional organ and,liver diseases,such as hepatitis,cirrhosis,liver cancer,create severe health-th......
Mutationsingenesencodingkeyplayersinoncogenicsignalingpathwaystriggerspecificdownstreamgeneexpressionprofilesintherespec......
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Hepatocytes in alginate microcapsules have been used to treat congenital liver enzyme deficiencies and acute liver f......
The protein phosphatase 1 complex is a direct target of AKT linking insulin signaling to hepatic gly
Insulin-stimulated hepatic glycogen synthesis is central to glucose homeostasis.Here,we identify that PPP1R3g,a regu......
Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing(
Background: The liver is the largest human internal organ-it is composed of multiple cell types and plays a vital ro......
体外原代培养犊牛肝细胞,添加0、16、64和128μg/L脂联素（adiponectin,ADPN）,分别培养4、8h后,提取细胞总RNA。应用实时荧光定量PCR......
为了探讨重组牛抵抗素对体外培养肝细胞PEPCK活性的影响,取72h培养良好的肝细胞培养板（6孔板）,每孔分别接种重组牛抵抗素0,10,50,100......
梗阻性黄疸可以启动肝细胞的凋亡程序,且有多种因素参与了梗阻性黄疸时肝细胞凋亡的发生过程,研究其机制对于梗阻性黄疸肝损伤的防......
Objective:To observe the effect of sodium citrate plasma (scP) on the growth and function of hepatocytes. Methods: HepG2......
砷是一种广泛分布于自然环境的污染物，肝脏是砷毒性的主要靶器官之一，砷通过影响肝细胞凋亡的失衡从而造成肝脏损伤并引起肝脏疾病，然......
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目的了解转录因子ETS-1介导亚砷酸钠（NaAsO2）对人正常肝细胞L-02的微小RNA（miRNA，miR）-21表达的影响。方法量-效关系研究：采用不同剂量Na......
AIM: The manner in which a cell responds to and influences its environment is ultimately determined by the genes that ar......
目的观察肝癌细胞HepG2与肝星状细胞(HSC)相互作用对二者生长状态的影响，初步探讨肝癌细胞和间质细胞的相互作用在肝癌发展过程中的......
目的探讨高脂肪饮食对Sprague Dawley(SD)大鼠雌性后代糖脂代谢和卵巢功能的影响。方法将雌雄大鼠按照2∶1的比例合笼交配，收集交配......
蛋白激酶C(PKC)是丝/苏氨酶激酶家族中的一种广泛分布于人体各种组织细胞中并参与多种激素和细胞因子细胞内信号传递的特殊激酶，在......
Uptake of albumin nanoparticle surface modified with glycyrrhizin by primary cultured rat hepatocyte
AIM: To investigate the uptake difference between bovine serum albumin nanoparticle (BSA-NP) and bovine serum albumin na......
AIM: To evaluate the effects of betaine on the ethanolinduced secretion of IGF-Ⅰ and IGFBP-1 using radioimmunoassay and......
Beneficial effect of an antibody against interleukin-2 receptor(daclizumab) in an experimental model
AIM: To investigate the use of Daclizumab (Dmab) as an immunosuppressive agent in an experimental model of hepatocyte xe......
ObjectiveTo investigate the effect of naphthalene acetic acid (NAA) on proliferation and apoptosis of mice hepatocytes.M......
Objective:To explore the cytotoxicity effects of Caspian cobra (Naja oxiana or N.oxiana) venom on hepatocytes and mitoch......
目的研究丙型肝炎病毒(HCV)核心蛋白对人源性肝细胞凋亡的影响。方法构建HCV核心蛋白真核表达载体pIRES-core,转染人源永生化肝细......
目的 探讨宿主和病毒因素在慢性乙型肝炎(CHB)患者肝细胞脂肪变中的作用.方法 将肝穿组织活检证实的562例CHB患者(男450例,女112例......
目的 探讨肝细胞移植对大鼠肝纤维化的改善作用及其机制.方法 经腹腔注射四氯化碳制备的肝纤维化Wistar大鼠接受正常Wistar大鼠肝......
目的 探索成人肝细胞的分离方法 以及培养条件.方法 在获取外科手术切除或不适宜肝移植的成人肝脏后,采用改良胶原酶P两步法分离成......
目的 探讨门静脉、尾静脉和肝动脉3种移植途径下大鼠骨髓干细胞迁移至肝脏及向肝细胞分化的情况.方法 取30只正常SD大鼠,采用2-乙......
目的 观察骨髓问充质细胞(BMCs)移植能否提高严重肝功能损害合并再生障碍的同种先天性无白蛋白大鼠(F344alb)肝再生和修复能力.方......
目的 观察体外与不同比例再生肝细胞共培养对结肠癌细胞增殖潜能及肝再生相关因子的影响.方法 70%肝切除大鼠模型术后24 h采用原位......
BACKGROUND:Currently, one of the tough problems for the application of bioartiifcial liver (BAL) is the shortage of suit......
LIPOPOLYSACCHARIDE－INDUCED CYTOTOXICITY AGAINST CULTURED MOUSE HEPATOCYTES AND THE ROLE OF NONPARENC
ＬＩＰＯＰＯＬＹＳＡＣＣＨＡＲＩＤＥ－ＩＮＤＵＣＥＤＣＹＴＯＴＯＸＩＣＩＴＹＡＧＡＩＮＳＴＣＵＬＴＵＲＥＤＭＯＵＳＥＨＥＰＡＴＯＣＹＴＥＳＡＮＤＴＨＥＲＯＬＥＯＦＮＯＮＰＡＲＥＮＣＨＹＭＡＬＬＩＶＥＲＣＥＬＬＳＷａｎｇＹｕｍｉｎｇ（王宇明）；Ｈｉｒｏ...
LIPOPOLYSACCHARIDE-INDUCEDCYTOTOXICITYAGAINSTCULTUREDMOUSEHEPATOCYTESANDTHEROLEOFNONPARENCHYMALLIVERCELLSWang......
研究表皮生长因子（ＥＧＦ）对四氯化碳（ＣＣｌ４）所致大鼠原代培养肝细胞损伤的作用．方法：丙氨酸转氨酶（ＡｌａＡＴ）和天门冬氨酸转氨酶（ＡｓｐＡＴ）活力及Ｋ＋浓度用自动生化分析仪测......
The interplay between non-esterified fatty acids and bovine peroxisome proliferator-activated recept
Background:In dairy cows circulating non-esterified fatty acids (NEFA) increase early post-partum while liver and other ......
