myelin相关论文
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction and comm......
Recombinanthumanerythropoietinprotectingneuronand promotingmyelinrepairandfunctionalrecove
Purpose:Theaimofthisstudywastoobserverecombinanthumanerythropoie(rhEPO)onacutespinalcord compressiveinjuryinrats.......
Neurotrophin-4 induces myelin protein zero expression in cultured Schwann cells via TrkB/PI3K/Akt/mT
Myelin formation during peripheral nervous system development, and reformation after injury and in disease, requires mul......
B-cell CLL/lymphoma 11B(Bcl11b),as known as CTIP2,is a C2H2 zinc finger transcriptional factor,functions as a haploinsuf......
Akt(protein kinase B)plays important roles in various biological processes.Recent evidence has shown that mutations on A......
Combination treatment of EGb761 and methylprednisolone reduces tissue damage and improves functional
Methylprednisolone (MP) has been widely used as a standard therapeutic agent for the treatment of spinal cord injury (SC......
Regulatory effects of macrophages on the microenvironment in the damage zone after spinal cord injur
Mouse bone marrow-derived macrophages and fetal brain-derived microglia were isolated and cultured in vitro, then admini......
Stage-dependent regulation of oligodendrocyte differentiation and myelin gene expression by Nkx2.2 t
Nkx2.2 homeodomain transcriptional factor is initially expressed in differentiating oligodendrocyte precursor cells (OPC......
Myelin is essential for the normal function of the vertebrate central nervous system (CNS) and its destruction contribut......
Design,Synthesis and Evaluation of Nile Red Analogs for Myelin Imaging as Potential Near Infrared Im
Myelination is one of the fundamental biological processes in the vertebrate nervous system.Direct detection and quantif......
OBJECTIVE Nicotinamide phos⁃phoribosyltransferase(NAMPT)is the key enzyme for the synthesis of nicotinamide ade⁃nine d......
MYRF:A Mysterious Membrane-bound Transcription Factor Involved in Myelin Development and Human Disea
The myelin regulatory factor gene(MYRF)encodes a protein evolutionarily conserved from invertebrates to vertebrates,repr......
Clemastine rescues behavioral changes and enhances remyelination in the cuprizone mouse model of dem
Increasing evidence suggests that white matter disorders based on myelin sheath impairment may underlie the neuropatholo......
Neuregulin-1 type III is a key regulator in Schwann cell proliferation, committing to a myelinating fate and regulating ......
Contents of myelin-basic protein and S-100 in serum and brain tissue of neonatal rats with intrauter
BACKGROUND: The change of the content of myelin basic protein (MBP) in serum and brain tissue is the biochemical diadyna......
Immunization with inactivated autoreactive T cells(T cell vaccination) selected from individual’s own T cellrepertoire......
The stereoselecfive synthesis of typhoniside,a new cerebrosideisolated from Typhonium giganteum Engl,was accomplished.C......
Since disability in multiple sclerosis(MS) is a product of neurodegeneration and deficient remyelination, the ability to......
Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple scleros
Hydroxycitric acid(HCA) is derived primarily from the Garcinia plant and is widely used for its anti-inflammatory effect......
Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripo
Multiple sclerosis(MS) is an autoimmune disease of the central nervous system(CNS), with focal T lymphocytic infiltratio......
Neuroprotective effects of a ketogenic diet in combination with exogenous ketone salts following acu
We have previously shown that induction of ketosis by ketogenic diet (KD) conveyed neuroprotection following spinal cord......
Previous studies have shown that transplantation of human bone marrow mesenchymal stem cells promotes neural functional ......
Salvianolic acid B, an active pharmaceutical compound present inSalvia miltiorrhiza, exerts a neuroprotective effect in ......
Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular
The development, maturation and regeneration of Schwann cells (SCs), the main glial cells of the periph-eral nervous sys......
[目的]研究大鼠鼻粘膜来源干细胞(REMSCs)分化为施万样细胞与PC12高分化细胞共培养后髓鞘形成及轴突生长情况.[方法]取大鼠鼻甲组......
Genetic factors may be learnt from families with gene mutations that render nerve-injury sus-ceptibility even to ordinar......
Schizophrenia,as a common mental disease,seriously threatens the physical and mental health of human beings.It is charac......
Amyloid precursor protein and growth-associated protein 43 expression in brain white matter and spin
Studies have demonstrated that amyloid precursor protein(APP)expression increases in multiple sclerosis tissues during a......
Carnosine is a dipeptide that scavenges free radicals,inhibits inflammation in the central nervous system,and protects a......
Inflammatory cytokine and iNOS mRNA expression in mononuclear blood cells from patients with multipl
Multiple sclerosis (MS) is an inflammatory demyelination disease of unknown cause. Autoimmunity dh’ected by myelin is ......
Peripheral clonal deletion of MBP-specific T cells by intravenous au-toantigen: rapid reversal of on
Experimental autoimmune encephalomyelitis can be initiated spontaneously and developed progressively in TCR transgenic m......
Experimental autoimmune encephalomyelitis(EAE) is a good model for human multiple sclerosis(MS)research.However,there a......
Antibodies against native glycosylated myelin-oligodendroc- yte-glycoprotein (MOG) were measured by ELISA in patients wi......
BACKGROUND: The removal of degenerated axonal debris during Wallerian degeneration is very important for nerve regenerat......
Golli(genes of the oligodendrocyte lineage)蛋白是继经典MBP(myelin basic protein)后发现的由MBP基因编码的又一蛋白家族,其结......
BACKGROUND: Nogo protein has been identified as an inhibitor of axonal growth, which was highly expressed in central ner......
Effect of olfactory ensheathing cell transplantation on myelin repair and motor function in a rat mo
BACKGROUND:Olfactory ensheathing cell transplantation can activate axonal regeneration and enhance myelin repair,which a......
The inhibitor of DNA binding 2 is highly Expressed During the Late Stages of Myelination in Corpus C
act-Our previous study showed much Id2-immunore-activity in white matter region, ninety percent of Id2 immunoreac-tivity......
Effects of diethyldithiocarbamate on myelin basic protein expression in the rat lateral olfactory tr
BACKGROUND:Dithiocarbamates can cause demyelination of axons in the peripheral nervous system.Its derivate,diethyldithio......
少突胶质细胞作为中枢神经系统的髓鞘形成细胞,在体外培养时形成一个精细的突起网络,细胞生长并中止于富含髓鞘相关蛋白和脂质的膜......
Peripheral nerve injury in humans often leads to permanent functional deficits.Schwann cells play an important role in t......
成年哺乳动物中枢神经系统损伤后神经元轴突的再生能力极为有限,其中抑制性因素起重要作用,Nogo基因是近些年来发现的新的轴突再生......
Ameliorative effects of human adipose tissue-derived mesenchymal stem cells on myelin basic protein-
Mesenchymal stem cells have been previously shown to exert an immunomodulatory function.The present study sought to inve......
Zuogui pills have been shown to attenuate the inflammatory reaction in a rat model of experimental autoimmune encephalom......
A preliminary study by our research group showed that 6-mm-long regeneration chamber bridging is equivalent to autologou......
Objective To explore the correlations between serum uric acid(UA) levels and the clinical and cerebrospinal fluid(CSF) p......
髓鞘形成是一个包括协同性的胞吐、内吞、mRNA转运和细胞骨架的动态变化的复杂过程。尽管髓鞘的异常在溶酶体贮积症中很常见,但对......
Myelination by oligodendroglial cells (OLs) enables the propagation of action potentials along neuronal axons, which is ......
