clodronate相关论文
Oral Bisphosphonates Therapy for Osteogenesis Imperfecta: a Systematic Review and Meta-analysis of S
Objective To assess the effectiveness and safety of oral bisphosphonates in increasing bone mineral density (BMD), reduc......
Purpose Several clinical studies and experimental evidence have demonstrated that increased macrophage infiltration into......
据《The New England Journal ofMedicine》1998年339卷第6期报道 二磷酸酯是焦磷酸盐的同功异构体,因其抑制破骨细胞活力,故能有......
动物实验和初步临床研究提示，早期行clodrnate治疗能降低乳腺癌新发骨转移的发生率。为了解clodrnate对乳腺癌转移情况的历响，德国海......
实验旨在比较clodronate间断用药与持续用药对骨量和骨转换的影响。120例绝经后骨量减少妇女(平均年龄61岁)为实验组,另外30例妇......
目的 探讨clodronate 脂质体对急性坏死性胰腺炎(acute necrotizing pancreatitis,ANP)大鼠Kupffer 细胞(KC)凋亡的诱导作用.方法 ......
Macrophage depletion and Schwann cell transplantation reduce cyst size after rat contusive spinal co
Schwann cell transplantation is a promising therapy for the treatment of spinal cord injury (SCI) and is currently in cl......
In the central nervous system,immunologic surveillance and response are carried out,in large part,by microglia.These res......
Protective effect of clodronate-containing liposomes on intestinal mucosal injury in rats with sever
BACKGROUND: Severe acute pancreatitis (SAP) can result in intestinal mucosal injury. This study aimed to demonstrate the......
BACKGROUND:Studies have revealed that macrophages play an important role in the development of severe acute pancreatitis......
Background:Monocyte-derived fibrocytes play an important role in the progression of fibrosis in the skin,lungs,heart and......
AIM:To investigate the protective effect of clodronatecontaining liposomes against severe acute pancreatitis(SAP)-trigge......
目的 为了比较帕米膦酸二钠与氯甲膦酸二钠对骨转移所致高血钙和骨痛的治疗作用。方法将收治的有溶骨性骨转移病灶的７８例随机分为两......
目的：观察153钐-氯屈膦酸二钠（153Sm-clodronate）在原位人骨肉瘤裸鼠动物模型中的疗效。方法：以人骨肉瘤细胞系HOS-8603接种SCID小鼠皮......
为探讨脂质体色裹clodronate清除单核/巨噬细胞的作用,将clodronate用脂质体包裹,导入具有吞噬作用的单核/巨噬细胞内,使其在单核/......
为探讨脂质体色裹clodronate清除单核/巨噬细胞的作用,将clodronate用脂质体包裹,导入具有吞噬作用的单核/巨噬细胞内,使其在单核/......
目的：评价注射用唑来膦酸治疗恶性肿瘤骨转移疼痛的疗效和安全性。方法：54例患者随机分为治疗组和对照组：治疗组（28例）用唑来膦酸4mg加......
目的评价国产英卡膦酸二钠单次静脉滴注(注射剂)和连续口服(片剂)治疗恶性肿瘤骨转移疼痛的安全性,比较国产英卡膦酸二钠与国产氯......
目的 :评价骨膦和153钐乙二胺四甲撑磷酸 ( 153SmEDTMP)对头颈肿瘤骨转移灶单独及联合应用的效果及毒副作用。方法 :收治头颈肿瘤......
目的：对氯屈膦酸二钠的合成工艺进行了研究。方法：以二溴甲烷和亚膦酸三异丙酯为原料，经缩合、氯化、热裂解和成盐反应得到氯屈膦酸二......
