blood-brain相关论文
Magnetic resonance imaging under isoflurane anesthesia alters cortical cyclooxygenase-2 expression a
Background:Magnetic resonance imaging(MRI)of rodents combined with histol-ogy allows to determine what mechanisms underl......
Research Progresses in the Inhibitory Effect of Bone Mesenchymal Stem Cell-Derived Exosome on Blood-
Mesenchymal Stem Cells (MSCs) are a type of non-hematopoietic progenitor cells which have self-replication capacity and ......
Escape from abluminal LRP1-mediated clearance for boosted nanoparticle brain delivery and brain meta
Breast cancer brain metastases(BCBMs)are one of the most difficult malignancies to treat due to the intracranial locatio......
目的探讨超早期高压氧(hyperbaric oxygen, HBO)处理对持续脑缺血大鼠血脑屏障通透性的影响。方法健康雄性SD大鼠66只，按数字表法随......
目的研发一种新型爆震伤模拟装置建立小鼠脑爆震伤模型，并研究小鼠脑爆震伤的损伤机制。方法30只昆明小鼠随机（随机数字法）分为正常对......
Glucose transporter(GLUT)-mediated transcytosis has been validated as an efficient method to cross the blood-brain barri......
Intravenous injection of AAV-PHP.eB across the blood-brain barrier in the adult mouse for central ne
Objective To verify the neurotypicality of AAV-PHP.eB after tail vein injection in adult mice and its efficiency in cros......
Neuroimmune connections between corticotropinreleasing hormone and mast cells:novel strategies for t
Corticotropin-releasing hormone is a critical component of the hypothalamic–pituitary–adrenal axis,which plays a major......
ABC efflux transporters at blood-central nervous system barriers and their implications for treating
The barriers present in the interfaces between the blood and the central nervous system form a major hurdle for the phar......
目的探讨清开灵注射液抑制小胶质细胞缺氧活化后,脑微血管内皮细胞Toll样受体4 (TLR4)、gp91phox和闭锁小带蛋白-1 (ZO-1)的表达。......
缺氧通常会引起血脑屏障通透性增高,造成血管源性脑水肿加重神经元损伤.脑微血管内皮细胞之间的紧密连接是血脑屏障的结构和功能基......
目的观察银杏叶提取物对模拟高原低氧暴露下大鼠脑微血管渗漏的干预作用。方法大鼠随机分为3组,银杏叶提取物干预组大鼠在缺氧前3d......
目的观察大鼠脑出血后血肿周围RhoGTP酶（RhoA）的表达变化及地佐环平（dizo—cilpine，MK-801）对其表达的影响，探讨在脑出血后脑损伤中N-甲......
The experimental models of craniocercbral wounds caused by 7. 62 mm bullets, i. e. thepenetrating craniocerebral injury,......
Effect of anisodamine on changes of blood-brain barrier permeability following brain injury in rabbi
The changes of blood-brain barrier(BBB)permeability following brain injury werestudied quantitatively by using colloidal......
Potential therapeutic molecular targets for blood-brain barrier disruption after subarachnoid hemorr
Aneurysmal subarachnoid hemorrhage remains serious hemorrhagic stroke with high morbidities and mortalities.Aneurysm rup......
Alzheimer's disease(AD)is an increasingly common neurodegenerative disease.Since the intestinal microbiome is closel......
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygena
Calculus bovis is commonly used for the treatment of stroke in traditional Chinese medicine. Hyodeoxycholic acid(HDCA) i......
The brain is protected from the entry of foreign substances by blood-brain barrier (BBB), but becomes a barrier while ch......
Studying Molecular Aspects of the Blood-Brain Barrier Using an in Vitro Model: Contribution of a Glo
A global proteomics strategy was initiated to decipher molecular mechanisms associated with the blood-brain barrier (BBB......
This paper reviews evidence that the presence of mast cells in specific sites of central nervous system, suggesting infl......
Synthesis of 11C-labeled capsaicin ([11C]-2) was accomplished by O-[11C]methylation with [11C]-methyl iodide to a corres......
探讨脑内毛细管的生长发育与形态结构和功能的关系。方法：用透射电镜对３５只不同发育时期小鼠血脑屏障建立过程中的超微结构及血管密度......
ＴｈｅｃｈａｎｇｅｓｏｆｎｅｕｒｏｎａｌＣａ<sup>２＋</sup>ｃｈａｎｎｅｌａｎｄｉｔｓｅｆｆｅｃｔｓｏｎＢＢＢｐｅｒｍｅａｂｉｌｉｔｙａｎｄｃｅｒｅｂｒａｌｅｄｅｍａ ａｓｓｏｃｉａｔｅｄｗｉｔｈｂｒａｉｎｉｎｊｕｒｙＸｕＲｕｘｉａｎｇ（徐如祥）；ＹｉＳｈ?........
In vitro and in vivo study of formulated valproic acid loaded nanoemulsion in rats for epilepsy trea
OBJECTIVE To investigate the in vitro and in vivo potential of formulated valproic acid-encapsulated nanoemulsion in ter......
Effect of Tong-Qiao-Huo-Xue decoction on the expressions of related proteins of the blood-brain barr
OBJECTIVE To evaluate the effects of Tong-Qiao-Huo-Xue decoction(TQHXD)on the bloodbrain barrier(BBB)permeability and th......
Intranasal administration of carbamazepine-loaded carboxymethyl chitosan nanoparticles for drug deli
Epilepsy is considered as a common and diverse set of chronic neurological disorders and its symptoms can be controlled ......
Glaucoma has been recently characterized as a member of the group of anoikis-related diseases.Anoikis,a form of apoptosi......
Intracerebral hemorrhage(ICH)remains the second-most common form of stroke with high morbidity and mortality.ICH can be ......
The protection effect of compatibility of baicalin and gardenoside on the blood-brain barrier damage
Aim To investigate the protection effect of the compatibility of baicalin and geniposide （7 ： 3 ） on blood-brain barrier （BB......
Inhibition of nitric oxide synthase aggravates brain injury in diabetic rats with traumatic brain in
Studies have shown that hyperglycemia aggravates brain damage by affecting vascular endothelial function. However, the p......
Ischemic cerebral stroke is a leading cause of death and disability globally.At present,thrombolytics,such as recombinan......
Scalp mechanical stimulation promotes moderate vasodilation and the permeability of blood-brain barr
OBJECTIVE Scalp mechanical stimulation, like combing, is one of the useful methods to keep brain health, which was histo......
为探求清开灵注射液治疗中风的机制。以家兔自体血凝块复制脑出血模型，用干湿比重法及原子吸收分光光度计分别检测脑组织水份与Ｎａ＾＋、Ｋ＾＋、......
Solute carriers(SLCs)are the largest family of transmembrane transporters that determine the exchange of various substan......
Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative dis
Neurodegenerative diseases including Alzheimer’s disease,Parkinson’s disease,Huntington disease and amyotrophic latera......
Chronic exposure to low doses of ozone similar to a day of high pollution in Mexico City causes a state of oxidative str......
Understanding the mechanism of oxidative stress is likely to yield new insights regarding the pathogenesis of Alzheimer......
Malignant brain tumors remain difficult to treat with chemotherapy because the blood–brain barrier (BBB) limits the amo......
Neuroprotective mechanism of TMP269, a selective class ⅡA histone deacetylase inhibitor, after cereb
TMP269 is a selective class ⅡA histone deacetylase inhibitor that has a protective effect on the central nervous system......
Repositioning of dipeptidyl peptidase-4 inhibitors and glucagon like peptide-1 agonists as potential
Repositioning of dipeptidyl peptidase-4 inhibitors and glucagon like peptide-1 receptor agonists is a breakthrough in th......
Regulatory mechanisms of AQP-4 on blood-brain barrier damage after cerebral ischemia reperfusion inj
Aquaporin-4 （AQP-4）, a water-channel protein,is highly expressed in the brain, which is important ele- ments in the format......
Attenuated blood-brain barrier dysfunction by XQ-1H following ischemic stroke in hyperlipidemic rats
Following ischemic stroke, blood-brain barrier （BBB） is disrupted and is further aggravated with the corresponding inciden......
