ASTROCYTE相关论文
目的:本实验选取脉冲电针和音乐电针干预慢性应激抑郁大鼠,对星形胶质细胞、谷氨酸代谢、谷氨酸转运体及受体,神经营养因子前体蛋......
Acupuncture is a medical treatment that has been widely practiced in China for over 3000 years, yet the neural mechanism......
A neurovascular unit-on-a-chip: culture and differentiation of human neural stem cells in a three-di
Biological studies typically rely on a simple monolayer cell culture, which does not reflect the complex functional char......
Elemene Emulsion Injection Administration Reduces Neuropathic Pain by Inhibiting Astrocytic NDRG2 Ex
Objective:To investigate the mechanisms underlying elemene-induced analgesia in rats with spared nerve injury (SNI).Meth......
Spinal cord injury represents a devastating central nervous system injury that could impair the mobility and sensory fun......
Long noncoding RNAs (lncRNAs) participate in many pathophysiological processes after traumatic brain injury by mediating......
Circular RNAs (circRNAs) are a class of conserved, endogenous non-coding RNAs that are involved in transcriptional and p......
Downregulation of EphB2 by RNA interference attenuates glial/fibrotic scar formation and promotes ax
The rapid formation of a glial/fibrotic scar is one of the main factors hampering axon growth after spinal cord injury. ......
Profile of the RNA in exosomes from astrocytes and microglia using deep sequencing: implications for
Glial cells play an important role in signal transduction, energy metabolism, extracellular ion homeostasis and neuropro......
Food deprivation can rescue obesity and over-weight-induced mood disorders,and promote mood per-formance in normal subje......
Regenerating functional new neurons in the adult mammalian central nervous system hasbeen proven to be very challenging ......
Study on the Correlation between Synaptic Reconstruction and Astrocyte after Ischemia and the Influe
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Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis afte
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Spatiotemporal Imaging of Cellular Energy Metabolism with Genetically-Encoded Fluorescent Sensors in
The brain has very high energy requirements and consumes 20％ of the oxygen and 25％ of the glucose in the human body.Theref......
Heat-stroke is a serious form of hyperthermia with high mortality,and can induce severe central nervous system disorders......
Early Activation of Astrocytes does not Affect Amyloid Plaque Load in an Animal Model of Alzheimer&#
Astrocytes are closely associated with Alzheimer\'s disease (AD).However,their precise roles in AD pathogenesis remain......
Astrocytic GABAB Receptors in Mouse Hippocampus Control Responses to Behavioral Challenges through A
Major depressive disorder (MDD) is a common mood disorder that affects almost 20％ of the global population.In addition,mu......
Expression of Phospho-MeCP2s in the Developing Rat Brain and Function of Postnatal MeCP2 in Cerebell
Abnormal expression and dysfunction of methyl-CpG binding protein 2 (MeCP2) cause Rett syndrome (RTT).The diverse phosph......
The enhancement and orientation of Schwann cells migrating across the Astrocyte - Schwann cell bound
Schwann cells (SCs) transplantation is an attractive strategy in the treatment of spinal cord injury (SCI), while in the......
Neural stem cell transplantation decreases neuroinflammation in a transgenic mouse model of Alzheime
Inammatory mediators. Our results showed that in NSC-injected APP/PS1 mice, activation of GFAP, Iba-1, TLR4 and TLR4 pat......
O-GlcNAc glycosylation of p27kip1 promotes formation of glial scar and functional recovery after spi
Objective:To study the effect of O-GlcNAc glycosylation of p27kip1 on spinal cord injury, and provide further evidence f......
To establish the astrocyte machinery-chemical damage model,and to evaluate effects of different concentrations of muscon......
Cerebral dopamine neurotrophic factor(CDNF)alleviates endoplasmic reticulum stress-induced cell dama
Background Astrocyte damage and the disorders of cytokine secretion induced by endoplasmic reticulum stress(ERS)are cruc......
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Since the molecular mechanism underlying cerebral edema is not clear,the treatment of cerebral edema has remained unchan......
Cultured astrocytes from Wistar rats are more susceptible to swelling induced by glutamate than thos
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Glutamate(Glu),the most important excitatory neurotransmitter in the central nervous system(CNS),mediates synaptic plast......
Astrocytes affect the sound properties of medial geniculate body neurons in unilateral cochlear abla
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EA alleviates depressive-like behaviors and pathological changes in hippocampus in chronic unpredict
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Precious studies have demonstrated that estrogen affects iron metabolism in peripheral tissues....
Amyloid plaques and tau tangles are common pathological hallmarks for Alzheimers disease(AD); however,reducing Aβ produ......
Background Adult cortex has long been regarded as “non-neurogenic”.Recent studies have indicated the occurrence of neu......
Methylene Blue improves the disruption of blood brain barrier and attenuates astroglia activation af
Methylene blue(MB)was first synthesized in 1876 and has been used as treatment for malaria,methemoglobinemia,and cyanide......
Aquaporin 1 specifically accumulate around astrocyte nuclear to mediates Glu-induced nuclear swellin
Objective Aquaporins (AQPs) belong to the water-specific channel protein family and have been reported to involve in cel......
Metastasis is the principal cause of the morbidity and death of cancer patients.Brain metastases occur in about 25%of al......
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Protective Effects of Ginsenoside Rg1 on LPS-induced Astrocyte Activation in cultured rat primary as
Ginsenoside Rg1,an active component of ginseng,has been shown to attenuate LPS-induced inflammatory responses in RAW267.......
Effects of potassium channel on neuronal apoptosis induced by oxygen-glucose deprivation with or wit
Aim: It was generally believed that excessive potassium efflux was one of the primary causes of neuronal injury after ce......
Aim: Astrocytic glutamate transporter GLAST plays a critical role in clearance of extracellular glutamate and prevention......
Up-regulation of astroglial lipid-sensitive two-pore domain potassium channel TREK-1 in rat CNS afte
The lipid-sensitive mechano-gated TREK-1 has been shown to be predominantly expressed in the CNS.However, its regional a......
DCPIB,a specific inhibitor of volume regulated anion channels (VRACs),inhibits astrocyte proliferati
Volume regulated anion channels (VRACs) are involved in regulating the proliferation and cell cycle progression of a num......
Neuroinflammation involving both astrocyte and microglia mediates mechanical allodynia induced by in
Objective Cancer pain, especially bone cancer pain, affects the life quality of cancer patients, and current treatments ......
Neuronal NR2B-containing NMDA receptor mediates astrocytic c-Jun N-terminal kinase activation in a r
Objective The N-methyl-D-aspartate receptor (NMDAR) in the superficial dorsal horn is implicated as a major contributor ......
A wealth of clinical data has established a strong co-morbidity between depression and epilepsy.However,little is known ......
Objective This study is to observe the mechanism of the astrocytes regulating activation of the neurons induced by hypot......
